Identification of novel Lynch syndrome mutations in Chinese patients with endometriod endometrial cancer

Identification of novel Lynch syndrome mutations in Chinese patients with endometriod endometrial cancer

Objective: Lynch syndrome (LS) predisposes patients to early onset endometrioid endometrial cancer (EEC). However, little is known about LS-related EEC in the Chinese population. The aim of this study was to investigate the prevalence of LS and to identify the specific variants of LS in Chinese pati...

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Bibliographic Details
Main Authors: Caixia Ren, Yan Liu, Yuxiang Wang, Yan Tang, Yawei Wei, Congrong Liu, Hongquan Zhang
Format: Article
Language:English
Published: China Anti-Cancer Association 2020-05-01
Series:Cancer Biology & Medicine
Subjects:
dna mismatch repair
endometrial endometrioid cancer
germline mutation
lynch syndrome
next-generation sequencing
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1622

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