Biochemical and Cytological Comparison of Keratocystic Odontogenic Tumours to Nonkeratinising Odontogenic Cysts Fluid
Aim: To evaluate the levels of albumin, prealbumin, total protein, inorganic phosphate and presence of keratinocytes in the cystic fluid for the diagnosis and appropriate treatment planning of keratocystic odontogenic tumours and other non keratinizing odontogenic cysts. Materials and Methods:...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2015-07-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/6195/12501_CE[Ra1]_F(AK)_PF1(PAK)_PFA(AK)_PF2(PAG).pdf |
| Summary: | Aim: To evaluate the levels of albumin, prealbumin, total protein,
inorganic phosphate and presence of keratinocytes in the cystic
fluid for the diagnosis and appropriate treatment planning of
keratocystic odontogenic tumours and other non keratinizing
odontogenic cysts.
Materials and Methods: Fifteen keratocystic odontogenic
tumour and 15 controls were studied. The cystic fluid was
aspirated and analysed to determine the levels of albumin,
prealbumin, total protein, inorganic phosphate and the presence
of keratinocytes. The data collected was statistically evaluated
using Mann Whitney U-Test and Student’s t-test.
Results: A highly significant difference (p<0.0001) was seen when
a comparison of Prealbumin, total protein, inorganic phosphate
and presence of keratinocytes was made between keratocystic
odontogenic tumour and non keratinizing odontogenic cysts.
The presence of albumin also showed a significant difference
(p<0.01).
Conclusion: A combined analysis of total protein, albumin,
prealbumin, inorganic phosphorous and detection of epithelial
squames may be used as a diagnostic adjunct in the preoperative
diagnosis of keratocystic odontogenic tumour in a minimally
invasive and highly accurate fashion. |
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| ISSN: | 2249-782X 0973-709X |