Hypertension, risk factors and coronary artery stenosis: A case-control study
Although hypertension is introduced as a major risk factor for cardiovascular diseases (CVDs), our knowledge about the nature of the association is hindered. The aim of this study was to assess the concurrent associations of several factors including serologic, anthropometric and coronary artery ste...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2019-02-01
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| Series: | Clinical and Experimental Hypertension |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10641963.2018.1462376 |
| _version_ | 1797681392184721408 |
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| author | Zahra Sedaghat Mohammadjavad Zibaeenejad Mohammad Fararouei |
| author_facet | Zahra Sedaghat Mohammadjavad Zibaeenejad Mohammad Fararouei |
| author_sort | Zahra Sedaghat |
| collection | DOAJ |
| description | Although hypertension is introduced as a major risk factor for cardiovascular diseases (CVDs), our knowledge about the nature of the association is hindered. The aim of this study was to assess the concurrent associations of several factors including serologic, anthropometric and coronary artery stenosis (CAS) with blood pressure. This is a case-control study on 163 hypertensive patients (SBP > 140 mmHg or DBP > 80 mmHg) and 227 healthy participants. All participants underwent angiography due to classic symptoms of CVDs. Controlling for other study variables, significant associations between CAS (OR yes/no = 1.99, 95%CI: 1.18–3.34 P = 0.006), BMI (kg/m2) (OR = 1.08, 95%CI: 1.03–1.14, P = 0.002) and age (year) (OR = 1.03, 95%CI = 1.005–1.05, p = 0.01) with hypertension were found. However, according to the results of the stratified analysis, no such associations were found among those with significant CAS. BMI and age were the only significant predictors of hypertension among participants with no CAS. Abdominal obesity was not remained in the final model regardless of the presence or absence of stenosis. As expected, stenosis itself was significantly associated with hypertension. This study suggested that BMI and age are the most powerful predictors of hypertension among those without CAS. As the result, it can be concluded that CAS alters the association between several factors and hypertension. |
| first_indexed | 2024-03-11T23:44:17Z |
| format | Article |
| id | doaj.art-b2a2ff4ecfe145b1b8b8aa41c2bba6f9 |
| institution | Directory Open Access Journal |
| issn | 1064-1963 1525-6006 |
| language | English |
| last_indexed | 2024-03-11T23:44:17Z |
| publishDate | 2019-02-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Clinical and Experimental Hypertension |
| spelling | doaj.art-b2a2ff4ecfe145b1b8b8aa41c2bba6f92023-09-19T15:19:27ZengTaylor & Francis GroupClinical and Experimental Hypertension1064-19631525-60062019-02-0141218118610.1080/10641963.2018.14623761462376Hypertension, risk factors and coronary artery stenosis: A case-control studyZahra Sedaghat0Mohammadjavad Zibaeenejad1Mohammad Fararouei2HIV/AIDS Research center, Shiraz University of Medical SciencesHIV/AIDS Research center, Shiraz University of Medical SciencesHIV/AIDS Research center, Shiraz University of Medical SciencesAlthough hypertension is introduced as a major risk factor for cardiovascular diseases (CVDs), our knowledge about the nature of the association is hindered. The aim of this study was to assess the concurrent associations of several factors including serologic, anthropometric and coronary artery stenosis (CAS) with blood pressure. This is a case-control study on 163 hypertensive patients (SBP > 140 mmHg or DBP > 80 mmHg) and 227 healthy participants. All participants underwent angiography due to classic symptoms of CVDs. Controlling for other study variables, significant associations between CAS (OR yes/no = 1.99, 95%CI: 1.18–3.34 P = 0.006), BMI (kg/m2) (OR = 1.08, 95%CI: 1.03–1.14, P = 0.002) and age (year) (OR = 1.03, 95%CI = 1.005–1.05, p = 0.01) with hypertension were found. However, according to the results of the stratified analysis, no such associations were found among those with significant CAS. BMI and age were the only significant predictors of hypertension among participants with no CAS. Abdominal obesity was not remained in the final model regardless of the presence or absence of stenosis. As expected, stenosis itself was significantly associated with hypertension. This study suggested that BMI and age are the most powerful predictors of hypertension among those without CAS. As the result, it can be concluded that CAS alters the association between several factors and hypertension.http://dx.doi.org/10.1080/10641963.2018.1462376hypertensionbmiblood pressureangiographycoronary artery stenos |
| spellingShingle | Zahra Sedaghat Mohammadjavad Zibaeenejad Mohammad Fararouei Hypertension, risk factors and coronary artery stenosis: A case-control study Clinical and Experimental Hypertension hypertension bmi blood pressure angiography coronary artery stenos |
| title | Hypertension, risk factors and coronary artery stenosis: A case-control study |
| title_full | Hypertension, risk factors and coronary artery stenosis: A case-control study |
| title_fullStr | Hypertension, risk factors and coronary artery stenosis: A case-control study |
| title_full_unstemmed | Hypertension, risk factors and coronary artery stenosis: A case-control study |
| title_short | Hypertension, risk factors and coronary artery stenosis: A case-control study |
| title_sort | hypertension risk factors and coronary artery stenosis a case control study |
| topic | hypertension bmi blood pressure angiography coronary artery stenos |
| url | http://dx.doi.org/10.1080/10641963.2018.1462376 |
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