MOBILIZATION OF STEM CELLS AFTER LIVER TRANSPLANTATION AND RESECTION

The review article analyses the published literature for mobilization of CD34/CD45 positive bone marrow cells into peripheral blood after liver injury. Recent investigations of mechanism of bone marrow stem cells mobiliza- tion into peripheral blood, role of the stem cells in recovery of injured liv...

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Main Authors: R. M. Kurabekova, O. M. Tsirulnikova, O. P. Shevchenko
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2010-06-01
Series:Vestnik Transplantologii i Iskusstvennyh Organov
Subjects:
Online Access:https://journal.transpl.ru/vtio/article/view/349
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author R. M. Kurabekova
O. M. Tsirulnikova
O. P. Shevchenko
author_facet R. M. Kurabekova
O. M. Tsirulnikova
O. P. Shevchenko
author_sort R. M. Kurabekova
collection DOAJ
description The review article analyses the published literature for mobilization of CD34/CD45 positive bone marrow cells into peripheral blood after liver injury. Recent investigations of mechanism of bone marrow stem cells mobiliza- tion into peripheral blood, role of the stem cells in recovery of injured liver and clinical studies of hematopoietic stem cells mobilization after liver transplantation and resection are discussed in the review. Recently some stu- dies have demonstrated that bone marrow stem cells can participate in recovery of liver tissue and functions after its injury. Mobilization of bone marrow stem cells into peripheral blood after liver injury is one of the possible evidence of such participation. The mobilization of bone marrow stem cells was shown in experimental models and in clinical investigations. However the issue is still controversial as there are publications which failed to find mobilization of bone marrow stem cells into peripheral blood after liver transplantation or resection in pa- tients. In this review we investigate and summarize recent research of the topic.
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spelling doaj.art-b2a6b2c9d7cb465090aeeae09726707a2023-03-13T10:37:21ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovVestnik Transplantologii i Iskusstvennyh Organov1995-11912010-06-01124869210.15825/1995-1191-2010-4-86-92292MOBILIZATION OF STEM CELLS AFTER LIVER TRANSPLANTATION AND RESECTIONR. M. Kurabekova0O. M. Tsirulnikova1O. P. Shevchenko2Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial OrgansAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial OrgansAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial OrgansThe review article analyses the published literature for mobilization of CD34/CD45 positive bone marrow cells into peripheral blood after liver injury. Recent investigations of mechanism of bone marrow stem cells mobiliza- tion into peripheral blood, role of the stem cells in recovery of injured liver and clinical studies of hematopoietic stem cells mobilization after liver transplantation and resection are discussed in the review. Recently some stu- dies have demonstrated that bone marrow stem cells can participate in recovery of liver tissue and functions after its injury. Mobilization of bone marrow stem cells into peripheral blood after liver injury is one of the possible evidence of such participation. The mobilization of bone marrow stem cells was shown in experimental models and in clinical investigations. However the issue is still controversial as there are publications which failed to find mobilization of bone marrow stem cells into peripheral blood after liver transplantation or resection in pa- tients. In this review we investigate and summarize recent research of the topic.https://journal.transpl.ru/vtio/article/view/349mobilization of stem cellsbone marrow stem cellscd34/cd45 positive cellsliver transplantationliver resection.
spellingShingle R. M. Kurabekova
O. M. Tsirulnikova
O. P. Shevchenko
MOBILIZATION OF STEM CELLS AFTER LIVER TRANSPLANTATION AND RESECTION
Vestnik Transplantologii i Iskusstvennyh Organov
mobilization of stem cells
bone marrow stem cells
cd34/cd45 positive cells
liver transplantation
liver resection.
title MOBILIZATION OF STEM CELLS AFTER LIVER TRANSPLANTATION AND RESECTION
title_full MOBILIZATION OF STEM CELLS AFTER LIVER TRANSPLANTATION AND RESECTION
title_fullStr MOBILIZATION OF STEM CELLS AFTER LIVER TRANSPLANTATION AND RESECTION
title_full_unstemmed MOBILIZATION OF STEM CELLS AFTER LIVER TRANSPLANTATION AND RESECTION
title_short MOBILIZATION OF STEM CELLS AFTER LIVER TRANSPLANTATION AND RESECTION
title_sort mobilization of stem cells after liver transplantation and resection
topic mobilization of stem cells
bone marrow stem cells
cd34/cd45 positive cells
liver transplantation
liver resection.
url https://journal.transpl.ru/vtio/article/view/349
work_keys_str_mv AT rmkurabekova mobilizationofstemcellsafterlivertransplantationandresection
AT omtsirulnikova mobilizationofstemcellsafterlivertransplantationandresection
AT opshevchenko mobilizationofstemcellsafterlivertransplantationandresection