Placing human gene families into their evolutionary context
Abstract Following the draft sequence of the first human genome over 20 years ago, we have achieved unprecedented insights into the rules governing its evolution, often with direct translational relevance to specific diseases. However, staggering sequence complexity has also challenged the developme...
Main Authors: | Alex Dornburg, Rittika Mallik, Zheng Wang, Moisés A. Bernal, Brian Thompson, Elspeth A. Bruford, Daniel W. Nebert, Vasilis Vasiliou, Laurel R. Yohe, Jeffrey A. Yoder, Jeffrey P. Townsend |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2022-11-01
|
Series: | Human Genomics |
Online Access: | https://doi.org/10.1186/s40246-022-00429-5 |
Similar Items
-
Update on the human and mouse lipocalin (LCN) gene family, including evidence the mouse Mup cluster is result of an “evolutionary bloom”
by: Georgia Charkoftaki, et al.
Published: (2019-02-01) -
Update of the keratin gene family: evolution, tissue-specific expression patterns, and relevance to clinical disorders
by: Minh Ho, et al.
Published: (2022-01-01) -
Evolutionary divergence and functions of the <it>ADAM </it>and <it>ADAMTS </it>gene families
by: Brocker Chad N, et al.
Published: (2009-10-01) -
Evolutionary divergence and functions of the human interleukin (IL) gene family
by: Brocker Chad, et al.
Published: (2010-10-01) -
Evolutionary divergence and functions of the human acyl-CoA thioesterase gene (<it>ACOT</it>) family
by: Brocker Chad, et al.
Published: (2010-08-01)