Identification of a novel autophagy-related prognostic signature and small molecule drugs for glioblastoma by bioinformatics

Identification of a novel autophagy-related prognostic signature and small molecule drugs for glioblastoma by bioinformatics

Abstract Objective To explore the autophagy-related prognostic signature (ARPs) via data mining in gene expression profiles for glioblastoma (GBM). Methods Using the Cancer Genome Atlas (TCGA) database, we obtained 156 GBM samples and 5 adjacent normal samples, and denoted them as discovery cohort....

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Bibliographische Detailangaben
Hauptverfasser: Dongjiao Wang, Yuxue Jiang, Tie Wang, Zhe Wang, Fei Zou
Format: Artikel
Sprache:English
Veröffentlicht: BMC 2022-05-01
Schriftenreihe:BMC Medical Genomics
Schlagworte:
Autophagy
Gene signature
Prognosis
Glioblastoma
Mutation
LASSO cox regression analysis
Online Zugang:https://doi.org/10.1186/s12920-022-01261-5

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