Diabetic Ketoacidosis associated with Steroid in a Renal Transplant Recipient
Post-transplant diabetes mellitus is a serious complication of organ transplantation. Post-transplant diabetes mellitus is a form of type 2 diabetes mellitus that is thought to develop in response to a relative insulin deficiency resulting from increased insulin resistance or impaired insulin produc...
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Format: | Article |
Language: | English |
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Galenos Yayinevi
2015-09-01
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Series: | İstanbul Medical Journal |
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http://imj.galenos.com.tr/archives/archive-detail/article-preview/diabetic-ketoacidosis-associated-with-steroid-in-a/20966
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author | Şimal Köksal Cevher Ezgi Çoşkun Yenigün Nihal Özkayar Nergiz Bayrakcı Fatih Dede |
author_facet | Şimal Köksal Cevher Ezgi Çoşkun Yenigün Nihal Özkayar Nergiz Bayrakcı Fatih Dede |
author_sort | Şimal Köksal Cevher |
collection | DOAJ |
description | Post-transplant diabetes mellitus is a serious complication of organ transplantation. Post-transplant diabetes mellitus is a form of type 2 diabetes mellitus that is thought to develop in response to a relative insulin deficiency resulting from increased insulin resistance or impaired insulin production or a combination of both. The clinical presentation varies from asymptomatic hyperglycemia to hyperosmolar dehydration or diabetic ketoacidosis. The onset of diabetes is associated with reduced graft function and patient survival. Immunosuppressive drugs, such as corticosteroids and calcineurin inhibitors (cyclosporine and tacrolimus), are known to be diabetogenic. However, the association of diabetic ketoacidosis with the use of systemic corticosteroids is infrequently reported. Here, we report a 27-year-old female recipient of a live renal transplant who developed diabetic ketoacidosis associated with short-term corticosteroid treatment. |
first_indexed | 2024-04-10T11:15:58Z |
format | Article |
id | doaj.art-b2b6cbc0eeba464f86c46dc22caa9008 |
institution | Directory Open Access Journal |
issn | 2619-9793 2148-094X |
language | English |
last_indexed | 2024-04-10T11:15:58Z |
publishDate | 2015-09-01 |
publisher | Galenos Yayinevi |
record_format | Article |
series | İstanbul Medical Journal |
spelling | doaj.art-b2b6cbc0eeba464f86c46dc22caa90082023-02-15T16:18:50ZengGalenos Yayineviİstanbul Medical Journal2619-97932148-094X2015-09-0116312512610.5152/imj.2015.5807613049054Diabetic Ketoacidosis associated with Steroid in a Renal Transplant RecipientŞimal Köksal Cevher0Ezgi Çoşkun Yenigün1Nihal Özkayar2Nergiz Bayrakcı3Fatih Dede4 Ankara Numune Eğitim ve Araştırma Hastanesi, Nefroloji Kliniği, Ankara, Türkiye Ankara Numune Eğitim ve Araştırma Hastanesi, Nefroloji Kliniği, Ankara, Türkiye Ankara Numune Eğitim ve Araştırma Hastanesi, Nefroloji Kliniği, Ankara, Türkiye Ankara Numune Eğitim ve Araştırma Hastanesi, Nefroloji Kliniği, Ankara, Türkiye Ankara Numune Eğitim ve Araştırma Hastanesi, Nefroloji Kliniği, Ankara, Türkiye Post-transplant diabetes mellitus is a serious complication of organ transplantation. Post-transplant diabetes mellitus is a form of type 2 diabetes mellitus that is thought to develop in response to a relative insulin deficiency resulting from increased insulin resistance or impaired insulin production or a combination of both. The clinical presentation varies from asymptomatic hyperglycemia to hyperosmolar dehydration or diabetic ketoacidosis. The onset of diabetes is associated with reduced graft function and patient survival. Immunosuppressive drugs, such as corticosteroids and calcineurin inhibitors (cyclosporine and tacrolimus), are known to be diabetogenic. However, the association of diabetic ketoacidosis with the use of systemic corticosteroids is infrequently reported. Here, we report a 27-year-old female recipient of a live renal transplant who developed diabetic ketoacidosis associated with short-term corticosteroid treatment. http://imj.galenos.com.tr/archives/archive-detail/article-preview/diabetic-ketoacidosis-associated-with-steroid-in-a/20966 Diabetes mellitusdiabetic ketoacidosiscorticosteroidrenal transplantation |
spellingShingle | Şimal Köksal Cevher Ezgi Çoşkun Yenigün Nihal Özkayar Nergiz Bayrakcı Fatih Dede Diabetic Ketoacidosis associated with Steroid in a Renal Transplant Recipient İstanbul Medical Journal Diabetes mellitus diabetic ketoacidosis corticosteroid renal transplantation |
title | Diabetic Ketoacidosis associated with Steroid in a Renal Transplant Recipient |
title_full | Diabetic Ketoacidosis associated with Steroid in a Renal Transplant Recipient |
title_fullStr | Diabetic Ketoacidosis associated with Steroid in a Renal Transplant Recipient |
title_full_unstemmed | Diabetic Ketoacidosis associated with Steroid in a Renal Transplant Recipient |
title_short | Diabetic Ketoacidosis associated with Steroid in a Renal Transplant Recipient |
title_sort | diabetic ketoacidosis associated with steroid in a renal transplant recipient |
topic | Diabetes mellitus diabetic ketoacidosis corticosteroid renal transplantation |
url |
http://imj.galenos.com.tr/archives/archive-detail/article-preview/diabetic-ketoacidosis-associated-with-steroid-in-a/20966
|
work_keys_str_mv | AT simalkoksalcevher diabeticketoacidosisassociatedwithsteroidinarenaltransplantrecipient AT ezgicoskunyenigun diabeticketoacidosisassociatedwithsteroidinarenaltransplantrecipient AT nihalozkayar diabeticketoacidosisassociatedwithsteroidinarenaltransplantrecipient AT nergizbayrakcı diabeticketoacidosisassociatedwithsteroidinarenaltransplantrecipient AT fatihdede diabeticketoacidosisassociatedwithsteroidinarenaltransplantrecipient |