Diabetic Ketoacidosis associated with Steroid in a Renal Transplant Recipient

Post-transplant diabetes mellitus is a serious complication of organ transplantation. Post-transplant diabetes mellitus is a form of type 2 diabetes mellitus that is thought to develop in response to a relative insulin deficiency resulting from increased insulin resistance or impaired insulin produc...

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Main Authors: Şimal Köksal Cevher, Ezgi Çoşkun Yenigün, Nihal Özkayar, Nergiz Bayrakcı, Fatih Dede
Format: Article
Language:English
Published: Galenos Yayinevi 2015-09-01
Series:İstanbul Medical Journal
Subjects:
Online Access: http://imj.galenos.com.tr/archives/archive-detail/article-preview/diabetic-ketoacidosis-associated-with-steroid-in-a/20966
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author Şimal Köksal Cevher
Ezgi Çoşkun Yenigün
Nihal Özkayar
Nergiz Bayrakcı
Fatih Dede
author_facet Şimal Köksal Cevher
Ezgi Çoşkun Yenigün
Nihal Özkayar
Nergiz Bayrakcı
Fatih Dede
author_sort Şimal Köksal Cevher
collection DOAJ
description Post-transplant diabetes mellitus is a serious complication of organ transplantation. Post-transplant diabetes mellitus is a form of type 2 diabetes mellitus that is thought to develop in response to a relative insulin deficiency resulting from increased insulin resistance or impaired insulin production or a combination of both. The clinical presentation varies from asymptomatic hyperglycemia to hyperosmolar dehydration or diabetic ketoacidosis. The onset of diabetes is associated with reduced graft function and patient survival. Immunosuppressive drugs, such as corticosteroids and calcineurin inhibitors (cyclosporine and tacrolimus), are known to be diabetogenic. However, the association of diabetic ketoacidosis with the use of systemic corticosteroids is infrequently reported. Here, we report a 27-year-old female recipient of a live renal transplant who developed diabetic ketoacidosis associated with short-term corticosteroid treatment.
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spelling doaj.art-b2b6cbc0eeba464f86c46dc22caa90082023-02-15T16:18:50ZengGalenos Yayineviİstanbul Medical Journal2619-97932148-094X2015-09-0116312512610.5152/imj.2015.5807613049054Diabetic Ketoacidosis associated with Steroid in a Renal Transplant RecipientŞimal Köksal Cevher0Ezgi Çoşkun Yenigün1Nihal Özkayar2Nergiz Bayrakcı3Fatih Dede4 Ankara Numune Eğitim ve Araştırma Hastanesi, Nefroloji Kliniği, Ankara, Türkiye Ankara Numune Eğitim ve Araştırma Hastanesi, Nefroloji Kliniği, Ankara, Türkiye Ankara Numune Eğitim ve Araştırma Hastanesi, Nefroloji Kliniği, Ankara, Türkiye Ankara Numune Eğitim ve Araştırma Hastanesi, Nefroloji Kliniği, Ankara, Türkiye Ankara Numune Eğitim ve Araştırma Hastanesi, Nefroloji Kliniği, Ankara, Türkiye Post-transplant diabetes mellitus is a serious complication of organ transplantation. Post-transplant diabetes mellitus is a form of type 2 diabetes mellitus that is thought to develop in response to a relative insulin deficiency resulting from increased insulin resistance or impaired insulin production or a combination of both. The clinical presentation varies from asymptomatic hyperglycemia to hyperosmolar dehydration or diabetic ketoacidosis. The onset of diabetes is associated with reduced graft function and patient survival. Immunosuppressive drugs, such as corticosteroids and calcineurin inhibitors (cyclosporine and tacrolimus), are known to be diabetogenic. However, the association of diabetic ketoacidosis with the use of systemic corticosteroids is infrequently reported. Here, we report a 27-year-old female recipient of a live renal transplant who developed diabetic ketoacidosis associated with short-term corticosteroid treatment. http://imj.galenos.com.tr/archives/archive-detail/article-preview/diabetic-ketoacidosis-associated-with-steroid-in-a/20966 Diabetes mellitusdiabetic ketoacidosiscorticosteroidrenal transplantation
spellingShingle Şimal Köksal Cevher
Ezgi Çoşkun Yenigün
Nihal Özkayar
Nergiz Bayrakcı
Fatih Dede
Diabetic Ketoacidosis associated with Steroid in a Renal Transplant Recipient
İstanbul Medical Journal
Diabetes mellitus
diabetic ketoacidosis
corticosteroid
renal transplantation
title Diabetic Ketoacidosis associated with Steroid in a Renal Transplant Recipient
title_full Diabetic Ketoacidosis associated with Steroid in a Renal Transplant Recipient
title_fullStr Diabetic Ketoacidosis associated with Steroid in a Renal Transplant Recipient
title_full_unstemmed Diabetic Ketoacidosis associated with Steroid in a Renal Transplant Recipient
title_short Diabetic Ketoacidosis associated with Steroid in a Renal Transplant Recipient
title_sort diabetic ketoacidosis associated with steroid in a renal transplant recipient
topic Diabetes mellitus
diabetic ketoacidosis
corticosteroid
renal transplantation
url http://imj.galenos.com.tr/archives/archive-detail/article-preview/diabetic-ketoacidosis-associated-with-steroid-in-a/20966
work_keys_str_mv AT simalkoksalcevher diabeticketoacidosisassociatedwithsteroidinarenaltransplantrecipient
AT ezgicoskunyenigun diabeticketoacidosisassociatedwithsteroidinarenaltransplantrecipient
AT nihalozkayar diabeticketoacidosisassociatedwithsteroidinarenaltransplantrecipient
AT nergizbayrakcı diabeticketoacidosisassociatedwithsteroidinarenaltransplantrecipient
AT fatihdede diabeticketoacidosisassociatedwithsteroidinarenaltransplantrecipient