BAM15 Relieves Neurodegeneration in Aged <i>Caenorhabditis elegans</i> and Extends Lifespan

BAM15 Relieves Neurodegeneration in Aged <i>Caenorhabditis elegans</i> and Extends Lifespan

BAM15 was recently screened as a protonophore uncoupler specifically for the mitochondrial membrane but not the plasma membrane. It is equally as potent as FCCP, but less toxic. Previously, mitochondrial uncoupling via DNP alleviates neurodegeneration in the nematode <i>Caenorhabditis elegans&...

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Bibliografische gegevens
Hoofdauteurs:	Injeong Cho, Hyun-Ok Song, Ha Eun Ji, Sungtae Yang, Jeong Hoon Cho
Formaat:	Artikel
Taal:	English
Gepubliceerd in:	MDPI AG 2022-11-01
Reeks:	Metabolites
Onderwerpen:	BAM15 mitochondrial uncoupler neurodegeneration aging <i>C. elegans</i>
Online toegang:	https://www.mdpi.com/2218-1989/12/11/1129

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