BAM15 Relieves Neurodegeneration in Aged <i>Caenorhabditis elegans</i> and Extends Lifespan

BAM15 Relieves Neurodegeneration in Aged <i>Caenorhabditis elegans</i> and Extends Lifespan

BAM15 was recently screened as a protonophore uncoupler specifically for the mitochondrial membrane but not the plasma membrane. It is equally as potent as FCCP, but less toxic. Previously, mitochondrial uncoupling via DNP alleviates neurodegeneration in the nematode <i>Caenorhabditis elegans&...

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Bibliographic Details
Main Authors:	Injeong Cho, Hyun-Ok Song, Ha Eun Ji, Sungtae Yang, Jeong Hoon Cho
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Series:	Metabolites
Subjects:	BAM15 mitochondrial uncoupler neurodegeneration aging <i>C. elegans</i>
Online Access:	https://www.mdpi.com/2218-1989/12/11/1129

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