The EXCEL Trial: The Surgeons’ Perspective

There have been several investigations comparing the efficacy of percutaneous coronary intervention and coronary artery bypass grafting surgery for treatment of left main stem disease. This includes the Evaluation of XIENCE versus Coronary Artery Bypass Graft Surgery for Effectiveness of Left Main R...

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Main Authors: Marjan Jahangiri, Krishna Mani, Martin T Yates, Justin Nowell
Format: Article
Language:English
Published: Radcliffe Medical Media 2020-11-01
Series:European Cardiology Review
Online Access:https://www.ecrjournal.com/articles/the-excel-trial-the-surgeons-perspective
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author Marjan Jahangiri
Krishna Mani
Martin T Yates
Justin Nowell
author_facet Marjan Jahangiri
Krishna Mani
Martin T Yates
Justin Nowell
author_sort Marjan Jahangiri
collection DOAJ
description There have been several investigations comparing the efficacy of percutaneous coronary intervention and coronary artery bypass grafting surgery for treatment of left main stem disease. This includes the Evaluation of XIENCE versus Coronary Artery Bypass Graft Surgery for Effectiveness of Left Main Revascularizaton (EXCEL) trial, which has garnered significant controversy surrounding its experimental design and reporting of its results. The authors review the methodology, results, caveats and statements on the EXCEL trial. They also review the other trials in the management of left main stem disease comparing percutaneous coronary intervention with coronary artery bypass grafting, as well as the SYNTAX score and its role in future guidelines for revascularisation. These findings have significant implications for current practice, influencing the growing role for multidisciplinary team meeting and allowing clinicians and patients to make the right choice.
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spelling doaj.art-b2bc6ceee53142b7abbc917baf0098022024-04-20T16:02:01ZengRadcliffe Medical MediaEuropean Cardiology Review1758-37561758-37642020-11-011510.15420/ecr.2020.34The EXCEL Trial: The Surgeons’ PerspectiveMarjan Jahangiri0Krishna Mani1Martin T Yates2Justin Nowell3Department of Cardiac Surgery, St. George’s Hospital, London, UKDepartment of Cardiac Surgery, St. George’s Hospital, London, UKDepartment of Cardiac Surgery, St. George’s Hospital, London, UKDepartment of Cardiac Surgery, St. George’s Hospital, London, UKThere have been several investigations comparing the efficacy of percutaneous coronary intervention and coronary artery bypass grafting surgery for treatment of left main stem disease. This includes the Evaluation of XIENCE versus Coronary Artery Bypass Graft Surgery for Effectiveness of Left Main Revascularizaton (EXCEL) trial, which has garnered significant controversy surrounding its experimental design and reporting of its results. The authors review the methodology, results, caveats and statements on the EXCEL trial. They also review the other trials in the management of left main stem disease comparing percutaneous coronary intervention with coronary artery bypass grafting, as well as the SYNTAX score and its role in future guidelines for revascularisation. These findings have significant implications for current practice, influencing the growing role for multidisciplinary team meeting and allowing clinicians and patients to make the right choice.https://www.ecrjournal.com/articles/the-excel-trial-the-surgeons-perspective
spellingShingle Marjan Jahangiri
Krishna Mani
Martin T Yates
Justin Nowell
The EXCEL Trial: The Surgeons’ Perspective
European Cardiology Review
title The EXCEL Trial: The Surgeons’ Perspective
title_full The EXCEL Trial: The Surgeons’ Perspective
title_fullStr The EXCEL Trial: The Surgeons’ Perspective
title_full_unstemmed The EXCEL Trial: The Surgeons’ Perspective
title_short The EXCEL Trial: The Surgeons’ Perspective
title_sort excel trial the surgeons perspective
url https://www.ecrjournal.com/articles/the-excel-trial-the-surgeons-perspective
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