Computational Modeling of the Neurofibromin-Stimulated Guanosine Triphosphate Hydrolysis by the KRas Protein

We report the results of computational studies of the guanosine triphosphate (GTP) hydrolysis in the active site of the KRas-NF1 protein complex, where KRas stands for the K-isoform of the Ras (ras sarcoma) protein and NF1 (neurofbromin-1) is the activating protein. The model system was constructed...

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Bibliographic Details
Main Authors: Igor Polyakov, Alexander Nemukhin
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Biophysica
Subjects:
Online Access:https://www.mdpi.com/2673-4125/3/2/25