Large-scale multi-omics analysis suggests specific roles for intragenic cohesin in transcriptional regulation

Cohesin complex is essential for transcriptional regulation and chromosome folding. Here the authors provide a large-scale multi-omics analysis suggesting that cohesin bound on gene bodies has a specific role in transcriptional regulation.

Bibliographic Details
Main Authors: Jiankang Wang, Masashige Bando, Katsuhiko Shirahige, Ryuichiro Nakato
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30792-9
Description
Summary:Cohesin complex is essential for transcriptional regulation and chromosome folding. Here the authors provide a large-scale multi-omics analysis suggesting that cohesin bound on gene bodies has a specific role in transcriptional regulation.
ISSN:2041-1723