Large-scale multi-omics analysis suggests specific roles for intragenic cohesin in transcriptional regulation
Cohesin complex is essential for transcriptional regulation and chromosome folding. Here the authors provide a large-scale multi-omics analysis suggesting that cohesin bound on gene bodies has a specific role in transcriptional regulation.
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-06-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-30792-9 |
| _version_ | 1818469490969542656 |
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| author | Jiankang Wang Masashige Bando Katsuhiko Shirahige Ryuichiro Nakato |
| author_facet | Jiankang Wang Masashige Bando Katsuhiko Shirahige Ryuichiro Nakato |
| author_sort | Jiankang Wang |
| collection | DOAJ |
| description | Cohesin complex is essential for transcriptional regulation and chromosome folding. Here the authors provide a large-scale multi-omics analysis suggesting that cohesin bound on gene bodies has a specific role in transcriptional regulation. |
| first_indexed | 2024-04-13T21:25:15Z |
| format | Article |
| id | doaj.art-b2c4f7cfab4041a894738fdd1fbc2be3 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-13T21:25:15Z |
| publishDate | 2022-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-b2c4f7cfab4041a894738fdd1fbc2be32022-12-22T02:29:21ZengNature PortfolioNature Communications2041-17232022-06-0113111310.1038/s41467-022-30792-9Large-scale multi-omics analysis suggests specific roles for intragenic cohesin in transcriptional regulationJiankang Wang0Masashige Bando1Katsuhiko Shirahige2Ryuichiro Nakato3Institute for Quantitative Biosciences, The University of TokyoInstitute for Quantitative Biosciences, The University of TokyoInstitute for Quantitative Biosciences, The University of TokyoInstitute for Quantitative Biosciences, The University of TokyoCohesin complex is essential for transcriptional regulation and chromosome folding. Here the authors provide a large-scale multi-omics analysis suggesting that cohesin bound on gene bodies has a specific role in transcriptional regulation.https://doi.org/10.1038/s41467-022-30792-9 |
| spellingShingle | Jiankang Wang Masashige Bando Katsuhiko Shirahige Ryuichiro Nakato Large-scale multi-omics analysis suggests specific roles for intragenic cohesin in transcriptional regulation Nature Communications |
| title | Large-scale multi-omics analysis suggests specific roles for intragenic cohesin in transcriptional regulation |
| title_full | Large-scale multi-omics analysis suggests specific roles for intragenic cohesin in transcriptional regulation |
| title_fullStr | Large-scale multi-omics analysis suggests specific roles for intragenic cohesin in transcriptional regulation |
| title_full_unstemmed | Large-scale multi-omics analysis suggests specific roles for intragenic cohesin in transcriptional regulation |
| title_short | Large-scale multi-omics analysis suggests specific roles for intragenic cohesin in transcriptional regulation |
| title_sort | large scale multi omics analysis suggests specific roles for intragenic cohesin in transcriptional regulation |
| url | https://doi.org/10.1038/s41467-022-30792-9 |
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