Interaction between Purkinje cells and inhibitory interneurons may create adjustable output waveforms to generate timed cerebellar output.

Interaction between Purkinje cells and inhibitory interneurons may create adjustable output waveforms to generate timed cerebellar output.

We develop a new model that explains how the cerebellum may generate the timing in classical delay eyeblink conditioning. Recent studies show that both Purkinje cells (PCs) and inhibitory interneurons (INs) have parallel signal processing streams with two time scales: an AMPA receptor-mediated fast...

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Bibliographic Details
Main Authors: Simon Hong, Lance M Optican
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2474676?pdf=render

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