Experimental evidence of the genetic hypothesis on the etiology of bicuspid aortic valve aortopathy in the hamster model

Experimental evidence of the genetic hypothesis on the etiology of bicuspid aortic valve aortopathy in the hamster model

Bicuspid aortopathy occurs in approximately 50% of patients with bicuspid aortic valve (BAV), the most prevalent congenital cardiac malformation. Although different molecular players and etiological factors (genetic and hemodynamic) have been suggested to be involved in aortopathy predisposition and...

Full description

Bibliographic Details
Main Authors: María Teresa Soto-Navarrete, Bárbara Pozo-Vilumbrales, Miguel Ángel López-Unzu, Carmen Rueda-Martínez, M. Carmen Fernández, Ana Carmen Durán, Francisco Javier Pavón-Morón, Jorge Rodríguez-Capitán, Borja Fernández
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
bicuspid aortic valve (BAV)
aortic dilatation
pathophysiology
etiology
animal model
hamster
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.928362/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.928362/full

Similar Items