Adverse effects of BMPR2 suppression in macrophages in animal models of pulmonary hypertension

Adverse effects of BMPR2 suppression in macrophages in animal models of pulmonary hypertension

Inflammatory cells contribute to irreversible damage in pulmonary arterial hypertension (PAH). We hypothesized that in PAH, dysfunctional BMPR2 signaling in macrophages contributes to pulmonary vascular injury and phenotypic changes via proinflammatory cytokine production. Studies were conducted in:...

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Bibliographic Details
Main Authors:	James West, Xinping Chen, Ling Yan, Santhi Gladson, James Loyd, Hamid Rizwan, Megha Talati
Format:	Article
Language:	English
Published:	Wiley 2020-03-01
Series:	Pulmonary Circulation
Online Access:	https://doi.org/10.1177/2045894019856483

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