A case of severe erythema nodosum induced by methimazole

Erythema nodosum (EN), is the most common variant of septal panniculitis and is possibly a delayed hypersensitivity reaction triggered by a wide range of antigenic stimuli. Hypersensitivity reactions due to medications have been recognized as a cause of 3–10% of EN cases. Case reports of EN associat...

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Main Authors: Selma Emre, Didem Ozdemir, Sibel Orhun, Goknur Kalkan, Sertac Sener
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Saudi Pharmaceutical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016416301323
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author Selma Emre
Didem Ozdemir
Sibel Orhun
Goknur Kalkan
Sertac Sener
author_facet Selma Emre
Didem Ozdemir
Sibel Orhun
Goknur Kalkan
Sertac Sener
author_sort Selma Emre
collection DOAJ
description Erythema nodosum (EN), is the most common variant of septal panniculitis and is possibly a delayed hypersensitivity reaction triggered by a wide range of antigenic stimuli. Hypersensitivity reactions due to medications have been recognized as a cause of 3–10% of EN cases. Case reports of EN associated with the anti-thyroid drugs are quite rarely reported in the literature even if there is a common use of anti-thyroid drugs. We report an EN case due to methimazole. The complaints of patients arose immediately fifteen days after the beginning of methimazole treatment. To the best of our knowledge, this case report is the first of an erythema nodosum induced by methimazole.
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spelling doaj.art-b2cf969fe4bc42c1b6b284645ed158d32022-12-22T03:38:01ZengElsevierSaudi Pharmaceutical Journal1319-01642017-07-0125581381510.1016/j.jsps.2016.11.003A case of severe erythema nodosum induced by methimazoleSelma Emre0Didem Ozdemir1Sibel Orhun2Goknur Kalkan3Sertac Sener4Yildirim Beyazit University, Ataturk Training and Research Hospital, Dermatology Clinic, Ankara, TurkeyYildirim Beyazit University, Ataturk Training and Research Hospital, Endocrinology Clinic, Ankara, TurkeyYildirim Beyazit University, Ataturk Training and Research Hospital, Pathology Department, Ankara, TurkeyYildirim Beyazit University, Ataturk Training and Research Hospital, Dermatology Clinic, Ankara, TurkeyYildirim Beyazit University, Ataturk Training and Research Hospital, Dermatology Clinic, Ankara, TurkeyErythema nodosum (EN), is the most common variant of septal panniculitis and is possibly a delayed hypersensitivity reaction triggered by a wide range of antigenic stimuli. Hypersensitivity reactions due to medications have been recognized as a cause of 3–10% of EN cases. Case reports of EN associated with the anti-thyroid drugs are quite rarely reported in the literature even if there is a common use of anti-thyroid drugs. We report an EN case due to methimazole. The complaints of patients arose immediately fifteen days after the beginning of methimazole treatment. To the best of our knowledge, this case report is the first of an erythema nodosum induced by methimazole.http://www.sciencedirect.com/science/article/pii/S1319016416301323Anti-thyroid drugsErythema nodosumMethimazole
spellingShingle Selma Emre
Didem Ozdemir
Sibel Orhun
Goknur Kalkan
Sertac Sener
A case of severe erythema nodosum induced by methimazole
Saudi Pharmaceutical Journal
Anti-thyroid drugs
Erythema nodosum
Methimazole
title A case of severe erythema nodosum induced by methimazole
title_full A case of severe erythema nodosum induced by methimazole
title_fullStr A case of severe erythema nodosum induced by methimazole
title_full_unstemmed A case of severe erythema nodosum induced by methimazole
title_short A case of severe erythema nodosum induced by methimazole
title_sort case of severe erythema nodosum induced by methimazole
topic Anti-thyroid drugs
Erythema nodosum
Methimazole
url http://www.sciencedirect.com/science/article/pii/S1319016416301323
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