Effect of storage on residue levels of enrofloxacin in muscle of rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus carpio)
Since fluoroquinolones are one of the most commonly used antibacterial drugs in aquaculture, there is a risk of their residues to be found in the treated fish. The objective of this study was to examine t he changes in enrofloxacin and ciprofloxacin levelsduring storage of rainbow trout and common c...
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| Format: | Article |
| Language: | English |
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Ss.Cyril and Methodius University, Skopje
2016-03-01
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| Series: | Macedonian Veterinary Review |
| Subjects: | |
| Online Access: | http://www.macvetrev.mk/2016-1/macvetrev-2016-0076.pdf |
| _version_ | 1811293355279122432 |
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| author | Ralica Kyuchukova Anelia Milanova Aleksandra Daskalova Deyan Stratev Lubomir Lashev Alexander Pavlov |
| author_facet | Ralica Kyuchukova Anelia Milanova Aleksandra Daskalova Deyan Stratev Lubomir Lashev Alexander Pavlov |
| author_sort | Ralica Kyuchukova |
| collection | DOAJ |
| description | Since fluoroquinolones are one of the most commonly used antibacterial drugs in aquaculture, there is a risk of their residues to be found in the treated fish. The objective of this study was to examine t he changes in enrofloxacin and ciprofloxacin levelsduring storage of rainbow trout and common carp muscle at -18 °C. The trout and carp were treated orally with a single dose of 10 mg/kg of enrofloxacin. Tissue samples were collected 24 h after the treatment and stored at -18 °C for 270 days either as a whole fish or as precut muscle samples. Results for trout revealed that in the precut samples enrofloxacin concentration decreased significantly only after 9 months of storage, whereas a significant decline in the ciprofloxacin level was observed much earlier (after 3 months). After 9 months of storage, the trout stored without being sliced and eviscerated showed significantly higher levels of both quinolones as compared to the precut muscle samples. The enrofloxacin levels in the carp musculature decreased considerably after 3 months of storage and stayed almost unchanged up to the end of the study, whereas the ciprofloxacin concentration continued to drop even after this period and after 270 days constituted 1/6 of the initial values. |
| first_indexed | 2024-04-13T05:00:05Z |
| format | Article |
| id | doaj.art-b2d66acc1d4947c29e206ece04fb3009 |
| institution | Directory Open Access Journal |
| issn | 1409-7621 1857-7415 |
| language | English |
| last_indexed | 2024-04-13T05:00:05Z |
| publishDate | 2016-03-01 |
| publisher | Ss.Cyril and Methodius University, Skopje |
| record_format | Article |
| series | Macedonian Veterinary Review |
| spelling | doaj.art-b2d66acc1d4947c29e206ece04fb30092022-12-22T03:01:22ZengSs.Cyril and Methodius University, SkopjeMacedonian Veterinary Review1409-76211857-74152016-03-013919710210.1515/macvetrev-2016-0076Effect of storage on residue levels of enrofloxacin in muscle of rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus carpio)Ralica Kyuchukova0Anelia Milanova1Aleksandra Daskalova2Deyan Stratev3Lubomir Lashev4Alexander Pavlov5Department of Hygiene and Technology of Foods,Faculty of Veterinary Medicine, Trakia University, BulgariaDepartment of Pharmacology, Physiology of Animals and Physiological Chemistry,Faculty of Veterinary Medicine, Trakia University, BulgariaDepartment of Hygiene and Technology of Foods,Faculty of Veterinary Medicine, Trakia University, BulgariaDepartment of Hygiene and Technology of Foods,Faculty of Veterinary Medicine, Trakia University, BulgariaDepartment of Pharmacology, Physiology of Animals and Physiological Chemistry,Faculty of Veterinary Medicine, Trakia University, BulgariaDepartment of Hygiene and Technology of Foods,Faculty of Veterinary Medicine, Trakia University, BulgariaSince fluoroquinolones are one of the most commonly used antibacterial drugs in aquaculture, there is a risk of their residues to be found in the treated fish. The objective of this study was to examine t he changes in enrofloxacin and ciprofloxacin levelsduring storage of rainbow trout and common carp muscle at -18 °C. The trout and carp were treated orally with a single dose of 10 mg/kg of enrofloxacin. Tissue samples were collected 24 h after the treatment and stored at -18 °C for 270 days either as a whole fish or as precut muscle samples. Results for trout revealed that in the precut samples enrofloxacin concentration decreased significantly only after 9 months of storage, whereas a significant decline in the ciprofloxacin level was observed much earlier (after 3 months). After 9 months of storage, the trout stored without being sliced and eviscerated showed significantly higher levels of both quinolones as compared to the precut muscle samples. The enrofloxacin levels in the carp musculature decreased considerably after 3 months of storage and stayed almost unchanged up to the end of the study, whereas the ciprofloxacin concentration continued to drop even after this period and after 270 days constituted 1/6 of the initial values.http://www.macvetrev.mk/2016-1/macvetrev-2016-0076.pdfciprofloxacincommon carpenrofloxacinrainbow troutresiduesstorage |
| spellingShingle | Ralica Kyuchukova Anelia Milanova Aleksandra Daskalova Deyan Stratev Lubomir Lashev Alexander Pavlov Effect of storage on residue levels of enrofloxacin in muscle of rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus carpio) Macedonian Veterinary Review ciprofloxacin common carp enrofloxacin rainbow trout residues storage |
| title | Effect of storage on residue levels of enrofloxacin in muscle of rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus carpio) |
| title_full | Effect of storage on residue levels of enrofloxacin in muscle of rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus carpio) |
| title_fullStr | Effect of storage on residue levels of enrofloxacin in muscle of rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus carpio) |
| title_full_unstemmed | Effect of storage on residue levels of enrofloxacin in muscle of rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus carpio) |
| title_short | Effect of storage on residue levels of enrofloxacin in muscle of rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus carpio) |
| title_sort | effect of storage on residue levels of enrofloxacin in muscle of rainbow trout oncorhynchus mykiss and common carp cyprinus carpio |
| topic | ciprofloxacin common carp enrofloxacin rainbow trout residues storage |
| url | http://www.macvetrev.mk/2016-1/macvetrev-2016-0076.pdf |
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