Binding and structural basis of equine ACE2 to RBDs from SARS-CoV, SARS-CoV-2 and related coronaviruses

Binding and structural basis of equine ACE2 to RBDs from SARS-CoV, SARS-CoV-2 and related coronaviruses

This study documents equine ACE2 (eqACE2) binding to the RBDs of SARS-CoV-2 and related CoVs, revealing a mechanism of eqACE2 binding with RaTG13-RBD, SARS-CoV-2 prototype-RBD and Omicron BA.1-RBD.

Bibliographic Details
Main Authors: Zepeng Xu, Xinrui Kang, Pu Han, Pei Du, Linjie Li, Anqi Zheng, Chuxia Deng, Jianxun Qi, Xin Zhao, Qihui Wang, Kefang Liu, George Fu Gao
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31276-6

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