β Thalassemia Mutation Flow in Indonesia: A Migration Perspective
Indonesia is a large island country with a wide variety of ethnic groups. As part of the thalassemia country belt, Indonesia has alleles that are as distinctive as those found in other parts of Southeast Asia. The journey of ancestors in the prehistoric period and the massive increase in human excha...
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Format: | Article |
Language: | English |
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MDPI AG
2023-12-01
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Series: | Thalassemia Reports |
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Online Access: | https://www.mdpi.com/2039-4365/13/4/22 |
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author | Lantip Rujito Ziske Maritska Abdul Salam Sofro |
author_facet | Lantip Rujito Ziske Maritska Abdul Salam Sofro |
author_sort | Lantip Rujito |
collection | DOAJ |
description | Indonesia is a large island country with a wide variety of ethnic groups. As part of the thalassemia country belt, Indonesia has alleles that are as distinctive as those found in other parts of Southeast Asia. The journey of ancestors in the prehistoric period and the massive increase in human exchange in the last decade have formed the current population of Indonesia. The mutants of the beta-thalassemia allele brought by those predecessors can be seen from the traces of their journey. This paperdescribes the flow gene according to the type of mutations of beta-thalassemia in the country. |
first_indexed | 2024-03-08T20:19:24Z |
format | Article |
id | doaj.art-b2e6b72c7600462ebebce48dd4f121ab |
institution | Directory Open Access Journal |
issn | 2039-4365 |
language | English |
last_indexed | 2024-03-08T20:19:24Z |
publishDate | 2023-12-01 |
publisher | MDPI AG |
record_format | Article |
series | Thalassemia Reports |
spelling | doaj.art-b2e6b72c7600462ebebce48dd4f121ab2023-12-22T14:45:45ZengMDPI AGThalassemia Reports2039-43652023-12-0113425326110.3390/thalassrep13040022β Thalassemia Mutation Flow in Indonesia: A Migration PerspectiveLantip Rujito0Ziske Maritska1Abdul Salam Sofro2Faculty of Medicine, Universitas Jenderal Soedirman, Jl Gumbreg 1, Purwokerto 53112, IndonesiaFaculty of Medicine, Universitas Sriwijaya, Jl. Srijaya Negara, Bukit Lama, Palembang 30139, IndonesiaFaculty of Medicine, Universitas YARSI, Jl. Letjen Suprapto No. Kav. 13, Jakarta 10510, IndonesiaIndonesia is a large island country with a wide variety of ethnic groups. As part of the thalassemia country belt, Indonesia has alleles that are as distinctive as those found in other parts of Southeast Asia. The journey of ancestors in the prehistoric period and the massive increase in human exchange in the last decade have formed the current population of Indonesia. The mutants of the beta-thalassemia allele brought by those predecessors can be seen from the traces of their journey. This paperdescribes the flow gene according to the type of mutations of beta-thalassemia in the country.https://www.mdpi.com/2039-4365/13/4/22beta-thalassemia alleleIndonesiagene flowmutant allelemigrationSoutheast Asia |
spellingShingle | Lantip Rujito Ziske Maritska Abdul Salam Sofro β Thalassemia Mutation Flow in Indonesia: A Migration Perspective Thalassemia Reports beta-thalassemia allele Indonesia gene flow mutant allele migration Southeast Asia |
title | β Thalassemia Mutation Flow in Indonesia: A Migration Perspective |
title_full | β Thalassemia Mutation Flow in Indonesia: A Migration Perspective |
title_fullStr | β Thalassemia Mutation Flow in Indonesia: A Migration Perspective |
title_full_unstemmed | β Thalassemia Mutation Flow in Indonesia: A Migration Perspective |
title_short | β Thalassemia Mutation Flow in Indonesia: A Migration Perspective |
title_sort | β thalassemia mutation flow in indonesia a migration perspective |
topic | beta-thalassemia allele Indonesia gene flow mutant allele migration Southeast Asia |
url | https://www.mdpi.com/2039-4365/13/4/22 |
work_keys_str_mv | AT lantiprujito bthalassemiamutationflowinindonesiaamigrationperspective AT ziskemaritska bthalassemiamutationflowinindonesiaamigrationperspective AT abdulsalamsofro bthalassemiamutationflowinindonesiaamigrationperspective |