β Thalassemia Mutation Flow in Indonesia: A Migration Perspective

Indonesia is a large island country with a wide variety of ethnic groups. As part of the thalassemia country belt, Indonesia has alleles that are as distinctive as those found in other parts of Southeast Asia. The journey of ancestors in the prehistoric period and the massive increase in human excha...

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Main Authors: Lantip Rujito, Ziske Maritska, Abdul Salam Sofro
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Thalassemia Reports
Subjects:
Online Access:https://www.mdpi.com/2039-4365/13/4/22
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author Lantip Rujito
Ziske Maritska
Abdul Salam Sofro
author_facet Lantip Rujito
Ziske Maritska
Abdul Salam Sofro
author_sort Lantip Rujito
collection DOAJ
description Indonesia is a large island country with a wide variety of ethnic groups. As part of the thalassemia country belt, Indonesia has alleles that are as distinctive as those found in other parts of Southeast Asia. The journey of ancestors in the prehistoric period and the massive increase in human exchange in the last decade have formed the current population of Indonesia. The mutants of the beta-thalassemia allele brought by those predecessors can be seen from the traces of their journey. This paperdescribes the flow gene according to the type of mutations of beta-thalassemia in the country.
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spelling doaj.art-b2e6b72c7600462ebebce48dd4f121ab2023-12-22T14:45:45ZengMDPI AGThalassemia Reports2039-43652023-12-0113425326110.3390/thalassrep13040022β Thalassemia Mutation Flow in Indonesia: A Migration PerspectiveLantip Rujito0Ziske Maritska1Abdul Salam Sofro2Faculty of Medicine, Universitas Jenderal Soedirman, Jl Gumbreg 1, Purwokerto 53112, IndonesiaFaculty of Medicine, Universitas Sriwijaya, Jl. Srijaya Negara, Bukit Lama, Palembang 30139, IndonesiaFaculty of Medicine, Universitas YARSI, Jl. Letjen Suprapto No. Kav. 13, Jakarta 10510, IndonesiaIndonesia is a large island country with a wide variety of ethnic groups. As part of the thalassemia country belt, Indonesia has alleles that are as distinctive as those found in other parts of Southeast Asia. The journey of ancestors in the prehistoric period and the massive increase in human exchange in the last decade have formed the current population of Indonesia. The mutants of the beta-thalassemia allele brought by those predecessors can be seen from the traces of their journey. This paperdescribes the flow gene according to the type of mutations of beta-thalassemia in the country.https://www.mdpi.com/2039-4365/13/4/22beta-thalassemia alleleIndonesiagene flowmutant allelemigrationSoutheast Asia
spellingShingle Lantip Rujito
Ziske Maritska
Abdul Salam Sofro
β Thalassemia Mutation Flow in Indonesia: A Migration Perspective
Thalassemia Reports
beta-thalassemia allele
Indonesia
gene flow
mutant allele
migration
Southeast Asia
title β Thalassemia Mutation Flow in Indonesia: A Migration Perspective
title_full β Thalassemia Mutation Flow in Indonesia: A Migration Perspective
title_fullStr β Thalassemia Mutation Flow in Indonesia: A Migration Perspective
title_full_unstemmed β Thalassemia Mutation Flow in Indonesia: A Migration Perspective
title_short β Thalassemia Mutation Flow in Indonesia: A Migration Perspective
title_sort β thalassemia mutation flow in indonesia a migration perspective
topic beta-thalassemia allele
Indonesia
gene flow
mutant allele
migration
Southeast Asia
url https://www.mdpi.com/2039-4365/13/4/22
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AT ziskemaritska bthalassemiamutationflowinindonesiaamigrationperspective
AT abdulsalamsofro bthalassemiamutationflowinindonesiaamigrationperspective