Broca's area network in language function.Broca's area network in language function: A pooling-data connectivity study
Background and Objective. Modern neuroimaging developments have demonstrated that cognitive functions correlate with brain networks rather than specific areas. The purpose of this paper was to analyze the connectivity of Broca's area based on language tasks. Methods. A connectivity modeling st...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2015-05-01
|
| Series: | Frontiers in Psychology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpsyg.2015.00687/full |
| _version_ | 1818335760051339264 |
|---|---|
| author | Byron eBernal Alfredo eArdila Monica eRosselli |
| author_facet | Byron eBernal Alfredo eArdila Monica eRosselli |
| author_sort | Byron eBernal |
| collection | DOAJ |
| description | Background and Objective. Modern neuroimaging developments have demonstrated that cognitive functions correlate with brain networks rather than specific areas. The purpose of this paper was to analyze the connectivity of Broca's area based on language tasks. Methods. A connectivity modeling study was performed by pooling data of Broca's activation in language tasks. Fifty-seven papers that included 883 subjects in 84 experiments were analyzed. Analysis of Likelihood Estimates of pooled data was utilized to generate the map; thresholds at p < 0.01 were corrected for multiple comparisons and false discovery rate. Resulting images were co-registered into MNI standard space. Results. A network consisting of 16 clusters of activation was obtained. Main clusters were located in the frontal operculum, left posterior temporal region, supplementary motor area, and the parietal lobe. Less common clusters were seen in the sub-cortical structures including the left thalamus, left putamen, secondary visual areas and the right cerebellum. Conclusions. BA44-related networks involved in language processing were demonstrated utilizing a pooling-data connectivity study. Significance, interpretation and limitations of the results are discussed. |
| first_indexed | 2024-12-13T14:28:32Z |
| format | Article |
| id | doaj.art-b2e8770d482440ebbb14a1a6134f3822 |
| institution | Directory Open Access Journal |
| issn | 1664-1078 |
| language | English |
| last_indexed | 2024-12-13T14:28:32Z |
| publishDate | 2015-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychology |
| spelling | doaj.art-b2e8770d482440ebbb14a1a6134f38222022-12-21T23:41:53ZengFrontiers Media S.A.Frontiers in Psychology1664-10782015-05-01610.3389/fpsyg.2015.00687133631Broca's area network in language function.Broca's area network in language function: A pooling-data connectivity studyByron eBernal0Alfredo eArdila1Monica eRosselli2Miami Children's HospitalFlorida International UniversityFlorida Atlantic UniversityBackground and Objective. Modern neuroimaging developments have demonstrated that cognitive functions correlate with brain networks rather than specific areas. The purpose of this paper was to analyze the connectivity of Broca's area based on language tasks. Methods. A connectivity modeling study was performed by pooling data of Broca's activation in language tasks. Fifty-seven papers that included 883 subjects in 84 experiments were analyzed. Analysis of Likelihood Estimates of pooled data was utilized to generate the map; thresholds at p < 0.01 were corrected for multiple comparisons and false discovery rate. Resulting images were co-registered into MNI standard space. Results. A network consisting of 16 clusters of activation was obtained. Main clusters were located in the frontal operculum, left posterior temporal region, supplementary motor area, and the parietal lobe. Less common clusters were seen in the sub-cortical structures including the left thalamus, left putamen, secondary visual areas and the right cerebellum. Conclusions. BA44-related networks involved in language processing were demonstrated utilizing a pooling-data connectivity study. Significance, interpretation and limitations of the results are discussed.http://journal.frontiersin.org/Journal/10.3389/fpsyg.2015.00687/fullBrainLanguageconnectivityfMRIfunctional connectivityphonology |
| spellingShingle | Byron eBernal Alfredo eArdila Monica eRosselli Broca's area network in language function.Broca's area network in language function: A pooling-data connectivity study Frontiers in Psychology Brain Language connectivity fMRI functional connectivity phonology |
| title | Broca's area network in language function.Broca's area network in language function: A pooling-data connectivity study |
| title_full | Broca's area network in language function.Broca's area network in language function: A pooling-data connectivity study |
| title_fullStr | Broca's area network in language function.Broca's area network in language function: A pooling-data connectivity study |
| title_full_unstemmed | Broca's area network in language function.Broca's area network in language function: A pooling-data connectivity study |
| title_short | Broca's area network in language function.Broca's area network in language function: A pooling-data connectivity study |
| title_sort | broca 39 s area network in language function broca 39 s area network in language function a pooling data connectivity study |
| topic | Brain Language connectivity fMRI functional connectivity phonology |
| url | http://journal.frontiersin.org/Journal/10.3389/fpsyg.2015.00687/full |
| work_keys_str_mv | AT byronebernal broca39sareanetworkinlanguagefunctionbroca39sareanetworkinlanguagefunctionapoolingdataconnectivitystudy AT alfredoeardila broca39sareanetworkinlanguagefunctionbroca39sareanetworkinlanguagefunctionapoolingdataconnectivitystudy AT monicaerosselli broca39sareanetworkinlanguagefunctionbroca39sareanetworkinlanguagefunctionapoolingdataconnectivitystudy |