Emerging Tick-Borne <i>Dabie bandavirus</i>: Virology, Epidemiology, and Prevention
Severe Fever with Thrombocytopenia Syndrome (SFTS), caused by <i>Dabie bandavirus</i> (SFTSV), is an emerging infectious disease first identified in China. Since its discovery, infections have spread throughout East Asian countries primarily through tick bites but also via transmission b...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/11/9/2309 |
| _version_ | 1797578760931770368 |
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| author | Eun-Ha Kim Su-Jin Park |
| author_facet | Eun-Ha Kim Su-Jin Park |
| author_sort | Eun-Ha Kim |
| collection | DOAJ |
| description | Severe Fever with Thrombocytopenia Syndrome (SFTS), caused by <i>Dabie bandavirus</i> (SFTSV), is an emerging infectious disease first identified in China. Since its discovery, infections have spread throughout East Asian countries primarily through tick bites but also via transmission between animals and humans. The expanding range of ticks, the primary vectors for SFTSV, combined with migration patterns of tick-carrying birds, sets the stage for the global spread of this virus. SFTSV rapidly evolves due to continuous mutation and reassortment; currently, no approved vaccines or antiviral drugs are available. Thus, the threat this virus poses to global health is unmistakable. This review consolidates the most recent research on SFTSV, including its molecular characteristics, transmission pathways through ticks and other animals, as well as the progress in antiviral drug and vaccine development, encompassing animal models and clinical trials. |
| first_indexed | 2024-03-10T22:26:25Z |
| format | Article |
| id | doaj.art-b2ed30feaa1f4c2e8808b2403262acdb |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-10T22:26:25Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-b2ed30feaa1f4c2e8808b2403262acdb2023-11-19T12:03:32ZengMDPI AGMicroorganisms2076-26072023-09-01119230910.3390/microorganisms11092309Emerging Tick-Borne <i>Dabie bandavirus</i>: Virology, Epidemiology, and PreventionEun-Ha Kim0Su-Jin Park1Center for Study of Emerging and Re-Emerging Viruses, Korea Virus Research Institute, Institute for Basic Science (IBS), Daejeon 34126, Republic of KoreaDivision of Life Science, Research Institute of Life Science, Gyeongsang National University, Jinju 52828, Republic of KoreaSevere Fever with Thrombocytopenia Syndrome (SFTS), caused by <i>Dabie bandavirus</i> (SFTSV), is an emerging infectious disease first identified in China. Since its discovery, infections have spread throughout East Asian countries primarily through tick bites but also via transmission between animals and humans. The expanding range of ticks, the primary vectors for SFTSV, combined with migration patterns of tick-carrying birds, sets the stage for the global spread of this virus. SFTSV rapidly evolves due to continuous mutation and reassortment; currently, no approved vaccines or antiviral drugs are available. Thus, the threat this virus poses to global health is unmistakable. This review consolidates the most recent research on SFTSV, including its molecular characteristics, transmission pathways through ticks and other animals, as well as the progress in antiviral drug and vaccine development, encompassing animal models and clinical trials.https://www.mdpi.com/2076-2607/11/9/2309severe fever with thrombocytopenia syndrome<i>Dabie bandavirus</i>public health |
| spellingShingle | Eun-Ha Kim Su-Jin Park Emerging Tick-Borne <i>Dabie bandavirus</i>: Virology, Epidemiology, and Prevention Microorganisms severe fever with thrombocytopenia syndrome <i>Dabie bandavirus</i> public health |
| title | Emerging Tick-Borne <i>Dabie bandavirus</i>: Virology, Epidemiology, and Prevention |
| title_full | Emerging Tick-Borne <i>Dabie bandavirus</i>: Virology, Epidemiology, and Prevention |
| title_fullStr | Emerging Tick-Borne <i>Dabie bandavirus</i>: Virology, Epidemiology, and Prevention |
| title_full_unstemmed | Emerging Tick-Borne <i>Dabie bandavirus</i>: Virology, Epidemiology, and Prevention |
| title_short | Emerging Tick-Borne <i>Dabie bandavirus</i>: Virology, Epidemiology, and Prevention |
| title_sort | emerging tick borne i dabie bandavirus i virology epidemiology and prevention |
| topic | severe fever with thrombocytopenia syndrome <i>Dabie bandavirus</i> public health |
| url | https://www.mdpi.com/2076-2607/11/9/2309 |
| work_keys_str_mv | AT eunhakim emergingtickborneidabiebandavirusivirologyepidemiologyandprevention AT sujinpark emergingtickborneidabiebandavirusivirologyepidemiologyandprevention |