Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques
Atherosclerosis is an important cause of cerebrovascular and cardiovascular disease (CVD). Lipid infiltration, inflammation, and altered vascular stress are the critical mechanisms that cause atherosclerotic plaque formation. The hallmarks of the progression of atherosclerosis include plaque ulcerat...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-10-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2023.1159288/full |
| _version_ | 1797660871692910592 |
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| author | Zhiwei He Jiaying Luo Mengna Lv Qingwen Li Wei Ke Xuan Niu Zhaohui Zhang |
| author_facet | Zhiwei He Jiaying Luo Mengna Lv Qingwen Li Wei Ke Xuan Niu Zhaohui Zhang |
| author_sort | Zhiwei He |
| collection | DOAJ |
| description | Atherosclerosis is an important cause of cerebrovascular and cardiovascular disease (CVD). Lipid infiltration, inflammation, and altered vascular stress are the critical mechanisms that cause atherosclerotic plaque formation. The hallmarks of the progression of atherosclerosis include plaque ulceration, rupture, neovascularization, and intraplaque hemorrhage, all of which are closely associated with the occurrence of CVD. Assessing the severity of atherosclerosis and plaque vulnerability is crucial for the prevention and treatment of CVD. Integrating imaging techniques for evaluating the characteristics of atherosclerotic plaques with computer simulations yields insights into plaque inflammation levels, spatial morphology, and intravascular stress distribution, resulting in a more realistic and accurate estimation of plaque state. Here, we review the characteristics and advancing techniques used to analyze intracranial and extracranial atherosclerotic plaques to provide a comprehensive understanding of atheroma. |
| first_indexed | 2024-03-11T18:37:09Z |
| format | Article |
| id | doaj.art-b2ed59a5e8ff48bc81a66dda4a6c89fc |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-03-11T18:37:09Z |
| publishDate | 2023-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-b2ed59a5e8ff48bc81a66dda4a6c89fc2023-10-12T18:00:36ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-10-011410.3389/fneur.2023.11592881159288Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniquesZhiwei He0Jiaying Luo1Mengna Lv2Qingwen Li3Wei Ke4Xuan Niu5Zhaohui Zhang6Department of Neurology, Renmin Hospital of Wuhan University, Wuhan, ChinaDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, ChinaDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, ChinaDepartment of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, ChinaDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, ChinaDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, ChinaDepartment of Neurology, Renmin Hospital of Wuhan University, Wuhan, ChinaAtherosclerosis is an important cause of cerebrovascular and cardiovascular disease (CVD). Lipid infiltration, inflammation, and altered vascular stress are the critical mechanisms that cause atherosclerotic plaque formation. The hallmarks of the progression of atherosclerosis include plaque ulceration, rupture, neovascularization, and intraplaque hemorrhage, all of which are closely associated with the occurrence of CVD. Assessing the severity of atherosclerosis and plaque vulnerability is crucial for the prevention and treatment of CVD. Integrating imaging techniques for evaluating the characteristics of atherosclerotic plaques with computer simulations yields insights into plaque inflammation levels, spatial morphology, and intravascular stress distribution, resulting in a more realistic and accurate estimation of plaque state. Here, we review the characteristics and advancing techniques used to analyze intracranial and extracranial atherosclerotic plaques to provide a comprehensive understanding of atheroma.https://www.frontiersin.org/articles/10.3389/fneur.2023.1159288/fullatherosclerosisbiomarkervulnerable plaqueplaque analysisimaging methodquantitative evaluation |
| spellingShingle | Zhiwei He Jiaying Luo Mengna Lv Qingwen Li Wei Ke Xuan Niu Zhaohui Zhang Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques Frontiers in Neurology atherosclerosis biomarker vulnerable plaque plaque analysis imaging method quantitative evaluation |
| title | Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques |
| title_full | Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques |
| title_fullStr | Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques |
| title_full_unstemmed | Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques |
| title_short | Characteristics and evaluation of atherosclerotic plaques: an overview of state-of-the-art techniques |
| title_sort | characteristics and evaluation of atherosclerotic plaques an overview of state of the art techniques |
| topic | atherosclerosis biomarker vulnerable plaque plaque analysis imaging method quantitative evaluation |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2023.1159288/full |
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