Neurobrucellosis presenting as an intra-medullary spinal cord abscess
<p>Abstract</p> <p>Background</p> <p>Of the diverse presentation of neurobrucellosis, intra-medullary spinal cord abscess is extremely rare. Only four other cases have been reported so far. We present a case of spinal cord intra-medullary abscess due to <it>Brucel...
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| Format: | Article |
| Language: | English |
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BMC
2005-09-01
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| Series: | Annals of Clinical Microbiology and Antimicrobials |
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| Online Access: | http://www.ann-clinmicrob.com/content/4/1/14 |
| _version_ | 1818522247486242816 |
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| author | Patil Chidanand S Nagmoti Mahantesh B Vajramani Girish V |
| author_facet | Patil Chidanand S Nagmoti Mahantesh B Vajramani Girish V |
| author_sort | Patil Chidanand S |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Of the diverse presentation of neurobrucellosis, intra-medullary spinal cord abscess is extremely rare. Only four other cases have been reported so far. We present a case of spinal cord intra-medullary abscess due to <it>Brucella melitensis</it>.</p> <p>Case presentation</p> <p>A forty-year-old female presented with progressive weakness of both lower limb with urinary incontinence of 6 months duration. She was febrile. Neurological examination revealed flaccid areflexic paraplegia with T<sub>10 </sub>below sensory impairment including perianal region. An intramedullary mass was diagnosed on Magnetic Resonance Image (MRI) scan extending from T<sub>12 </sub>to L<sub>2</sub>. At surgery, a large abscess was encountered at the conus medullaris, from which <it>Brucella melitensis </it>was grown on culture. She was started on streptomycin and doxycycline for 1 month, followed by rifampicin and doxycycline for 1 month. At 2-year follow-up, she had recovered only partially and continued to have impaired bladder function.</p> <p>Conclusion</p> <p>Neurobrucellosis, if not treated early, can result in severe neurological morbidity and sequale, which may be irreversible. Hence it is important to consider the possibility of neurobrucellosis in endemic region and treat aggressively.</p> |
| first_indexed | 2024-12-11T05:30:45Z |
| format | Article |
| id | doaj.art-b2f0e992d80944b1bf9b49feb61c9c7e |
| institution | Directory Open Access Journal |
| issn | 1476-0711 |
| language | English |
| last_indexed | 2024-12-11T05:30:45Z |
| publishDate | 2005-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Annals of Clinical Microbiology and Antimicrobials |
| spelling | doaj.art-b2f0e992d80944b1bf9b49feb61c9c7e2022-12-22T01:19:26ZengBMCAnnals of Clinical Microbiology and Antimicrobials1476-07112005-09-01411410.1186/1476-0711-4-14Neurobrucellosis presenting as an intra-medullary spinal cord abscessPatil Chidanand SNagmoti Mahantesh BVajramani Girish V<p>Abstract</p> <p>Background</p> <p>Of the diverse presentation of neurobrucellosis, intra-medullary spinal cord abscess is extremely rare. Only four other cases have been reported so far. We present a case of spinal cord intra-medullary abscess due to <it>Brucella melitensis</it>.</p> <p>Case presentation</p> <p>A forty-year-old female presented with progressive weakness of both lower limb with urinary incontinence of 6 months duration. She was febrile. Neurological examination revealed flaccid areflexic paraplegia with T<sub>10 </sub>below sensory impairment including perianal region. An intramedullary mass was diagnosed on Magnetic Resonance Image (MRI) scan extending from T<sub>12 </sub>to L<sub>2</sub>. At surgery, a large abscess was encountered at the conus medullaris, from which <it>Brucella melitensis </it>was grown on culture. She was started on streptomycin and doxycycline for 1 month, followed by rifampicin and doxycycline for 1 month. At 2-year follow-up, she had recovered only partially and continued to have impaired bladder function.</p> <p>Conclusion</p> <p>Neurobrucellosis, if not treated early, can result in severe neurological morbidity and sequale, which may be irreversible. Hence it is important to consider the possibility of neurobrucellosis in endemic region and treat aggressively.</p>http://www.ann-clinmicrob.com/content/4/1/14Neurobrucellosis<it>Brucella melitensis</it>spinal cordintra-medullary abscessMRI |
| spellingShingle | Patil Chidanand S Nagmoti Mahantesh B Vajramani Girish V Neurobrucellosis presenting as an intra-medullary spinal cord abscess Annals of Clinical Microbiology and Antimicrobials Neurobrucellosis <it>Brucella melitensis</it> spinal cord intra-medullary abscess MRI |
| title | Neurobrucellosis presenting as an intra-medullary spinal cord abscess |
| title_full | Neurobrucellosis presenting as an intra-medullary spinal cord abscess |
| title_fullStr | Neurobrucellosis presenting as an intra-medullary spinal cord abscess |
| title_full_unstemmed | Neurobrucellosis presenting as an intra-medullary spinal cord abscess |
| title_short | Neurobrucellosis presenting as an intra-medullary spinal cord abscess |
| title_sort | neurobrucellosis presenting as an intra medullary spinal cord abscess |
| topic | Neurobrucellosis <it>Brucella melitensis</it> spinal cord intra-medullary abscess MRI |
| url | http://www.ann-clinmicrob.com/content/4/1/14 |
| work_keys_str_mv | AT patilchidanands neurobrucellosispresentingasanintramedullaryspinalcordabscess AT nagmotimahanteshb neurobrucellosispresentingasanintramedullaryspinalcordabscess AT vajramanigirishv neurobrucellosispresentingasanintramedullaryspinalcordabscess |