Complex partial non-convulsive status epilepticus masquerading as hepatic encephalopathy: a case report

<p>Abstract</p> <p>Introduction</p> <p>Hepatic encephalopathy is usually suspected in patients who are cirrhotic with neuropsychiatric manifestations. We present a case of suspected hepatic encephalopathy that did not respond to standard empiric therapy and was eventual...

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Main Authors: Badshah Maaz B, Riaz Haris, Aslam Sana, Badshah Moaviz B, Korsten Mark A, Munir Muhammad Bilal
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Journal of Medical Case Reports
Subjects:
Online Access:http://www.jmedicalcasereports.com/content/6/1/422
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author Badshah Maaz B
Riaz Haris
Aslam Sana
Badshah Moaviz B
Korsten Mark A
Munir Muhammad Bilal
author_facet Badshah Maaz B
Riaz Haris
Aslam Sana
Badshah Moaviz B
Korsten Mark A
Munir Muhammad Bilal
author_sort Badshah Maaz B
collection DOAJ
description <p>Abstract</p> <p>Introduction</p> <p>Hepatic encephalopathy is usually suspected in patients who are cirrhotic with neuropsychiatric manifestations. We present a case of suspected hepatic encephalopathy that did not respond to standard empiric therapy and was eventually diagnosed as non-convulsive status epilepticus of complex partial type. Our patient responded dramatically to anti-convulsive therapy.</p> <p>Case presentation</p> <p>We report the case of a 45-year-old African-American man with hepatitis C virus cirrhosis and human immunodeficiency virus who presented to our facility with a one-day history of confusion and a variable mental status. Our patient’s vital signs were stable and all his electrolytes were within normal range. A clinical diagnosis of hepatic encephalopathy was made and our patient was started on empiric therapy with lactulose and rifaximin. Our patient did not respond to therapy. After five days of treatment, alternative diagnoses were sought and a neurology consult was requested. An electroencephalogram was eventually performed which showed seizure activity in the right parietal lobe. A diagnosis of non-convulsive status epilepticus was made and our patient was started on oral levetiracetam. On day two of therapy, our patient was alert and oriented. He continues to do well on follow-up approximately one year after discharge.</p> <p>Conclusions</p> <p>Non-convulsive status epilepticus should be considered in the differential diagnosis of patients with suspected hepatic encephalopathy who do not respond to empirical treatment. Further studies are needed to investigate the incidence of this entity in patients with persistent hepatic encephalopathy.</p>
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spelling doaj.art-b2f457fe7e72479ea01bd8d5df3bf7f32022-12-21T21:17:49ZengBMCJournal of Medical Case Reports1752-19472012-12-016142210.1186/1752-1947-6-422Complex partial non-convulsive status epilepticus masquerading as hepatic encephalopathy: a case reportBadshah Maaz BRiaz HarisAslam SanaBadshah Moaviz BKorsten Mark AMunir Muhammad Bilal<p>Abstract</p> <p>Introduction</p> <p>Hepatic encephalopathy is usually suspected in patients who are cirrhotic with neuropsychiatric manifestations. We present a case of suspected hepatic encephalopathy that did not respond to standard empiric therapy and was eventually diagnosed as non-convulsive status epilepticus of complex partial type. Our patient responded dramatically to anti-convulsive therapy.</p> <p>Case presentation</p> <p>We report the case of a 45-year-old African-American man with hepatitis C virus cirrhosis and human immunodeficiency virus who presented to our facility with a one-day history of confusion and a variable mental status. Our patient’s vital signs were stable and all his electrolytes were within normal range. A clinical diagnosis of hepatic encephalopathy was made and our patient was started on empiric therapy with lactulose and rifaximin. Our patient did not respond to therapy. After five days of treatment, alternative diagnoses were sought and a neurology consult was requested. An electroencephalogram was eventually performed which showed seizure activity in the right parietal lobe. A diagnosis of non-convulsive status epilepticus was made and our patient was started on oral levetiracetam. On day two of therapy, our patient was alert and oriented. He continues to do well on follow-up approximately one year after discharge.</p> <p>Conclusions</p> <p>Non-convulsive status epilepticus should be considered in the differential diagnosis of patients with suspected hepatic encephalopathy who do not respond to empirical treatment. Further studies are needed to investigate the incidence of this entity in patients with persistent hepatic encephalopathy.</p>http://www.jmedicalcasereports.com/content/6/1/422Hepatic encephalopathyNon-convulsive status epilepticusPartial seizuresElectroencephalogram
spellingShingle Badshah Maaz B
Riaz Haris
Aslam Sana
Badshah Moaviz B
Korsten Mark A
Munir Muhammad Bilal
Complex partial non-convulsive status epilepticus masquerading as hepatic encephalopathy: a case report
Journal of Medical Case Reports
Hepatic encephalopathy
Non-convulsive status epilepticus
Partial seizures
Electroencephalogram
title Complex partial non-convulsive status epilepticus masquerading as hepatic encephalopathy: a case report
title_full Complex partial non-convulsive status epilepticus masquerading as hepatic encephalopathy: a case report
title_fullStr Complex partial non-convulsive status epilepticus masquerading as hepatic encephalopathy: a case report
title_full_unstemmed Complex partial non-convulsive status epilepticus masquerading as hepatic encephalopathy: a case report
title_short Complex partial non-convulsive status epilepticus masquerading as hepatic encephalopathy: a case report
title_sort complex partial non convulsive status epilepticus masquerading as hepatic encephalopathy a case report
topic Hepatic encephalopathy
Non-convulsive status epilepticus
Partial seizures
Electroencephalogram
url http://www.jmedicalcasereports.com/content/6/1/422
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