Sexual Dysfunction in Female Patients with Type 2 Diabetes Mellitus—Sneak Peek on an Important Quality of Life Determinant

Type 2 diabetes mellitus (T2DM) is a multisystemic disease with a high global burden and chronic complications. Sexual dysfunction (SD) in patients with T2DM is an often-overlooked complication, despite its high impact on quality of life (QoL). Female sexual disorders can affect women of reproductiv...

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Main Authors: Marija Rogoznica, Dražen Perica, Barbara Borovac, Andrej Belančić, Martina Matovinović
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Diabetology
Subjects:
Online Access:https://www.mdpi.com/2673-4540/4/4/46
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author Marija Rogoznica
Dražen Perica
Barbara Borovac
Andrej Belančić
Martina Matovinović
author_facet Marija Rogoznica
Dražen Perica
Barbara Borovac
Andrej Belančić
Martina Matovinović
author_sort Marija Rogoznica
collection DOAJ
description Type 2 diabetes mellitus (T2DM) is a multisystemic disease with a high global burden and chronic complications. Sexual dysfunction (SD) in patients with T2DM is an often-overlooked complication, despite its high impact on quality of life (QoL). Female sexual disorders can affect women of reproductive age as well as menopausal women. Proposed mechanisms are intertwining a variety of physiological, neurological, vascular, hormonal, and psychological variables. The impairment of sexual function has been linked to hyperglycemia, insulin resistance, chronic low-grade inflammation, endothelial dysfunction, neuropathy, and hormonal abnormalities. There are many different manifestations of female sexual dysfunction, such as insufficient sexual desire, diminished arousal, difficulty in eliciting orgasm, and pain during sexual engagement. Numerous studies have shown that the QoL of patients living with diabetes mellitus (DM) is lower than that of those without DM. SD in women with T2DM leads to deteriorated QoL. Treatment must be individualized based on the diagnosis and the sexual dysfunction as well as underlying medical, psychological, and interpersonal issues. The goal of modern medical care for patients living with diabetes is not to delay death but to improve their health and QoL. The present review article aimed to raise awareness about female sexual dysfunction in patients with T2DM and to provide an overview of its impact on QoL.
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spelling doaj.art-b2f73e40a9c6431c979f5e746bf912342023-12-22T14:02:58ZengMDPI AGDiabetology2673-45402023-11-014452753610.3390/diabetology4040046Sexual Dysfunction in Female Patients with Type 2 Diabetes Mellitus—Sneak Peek on an Important Quality of Life DeterminantMarija Rogoznica0Dražen Perica1Barbara Borovac2Andrej Belančić3Martina Matovinović4Department of Physical Medicine, Rehabilitation and Rheumatology, Thalassotherapia Opatija, Maršala Tita 188, 51410 Opatija, CroatiaDepartment of Internal Medicine, Division of Metabolic Diseases, University Hospital Center Zagreb, Kišpatićeva 12, 10000 Zagreb, CroatiaDepartment of Gynecology and Obstetrics, Clinical Hospital Centre Rijeka, Krešimirova 42, 51000 Rijeka, CroatiaDepartment of Clinical Pharmacology, Clinical Hospital Centre Rijeka, Krešimirova 42, 51000 Rijeka, CroatiaDepartment of Internal Medicine, Division of Endocrinology, University Hospital Center Zagreb, Kišpatićeva 12, 10000 Zagreb, CroatiaType 2 diabetes mellitus (T2DM) is a multisystemic disease with a high global burden and chronic complications. Sexual dysfunction (SD) in patients with T2DM is an often-overlooked complication, despite its high impact on quality of life (QoL). Female sexual disorders can affect women of reproductive age as well as menopausal women. Proposed mechanisms are intertwining a variety of physiological, neurological, vascular, hormonal, and psychological variables. The impairment of sexual function has been linked to hyperglycemia, insulin resistance, chronic low-grade inflammation, endothelial dysfunction, neuropathy, and hormonal abnormalities. There are many different manifestations of female sexual dysfunction, such as insufficient sexual desire, diminished arousal, difficulty in eliciting orgasm, and pain during sexual engagement. Numerous studies have shown that the QoL of patients living with diabetes mellitus (DM) is lower than that of those without DM. SD in women with T2DM leads to deteriorated QoL. Treatment must be individualized based on the diagnosis and the sexual dysfunction as well as underlying medical, psychological, and interpersonal issues. The goal of modern medical care for patients living with diabetes is not to delay death but to improve their health and QoL. The present review article aimed to raise awareness about female sexual dysfunction in patients with T2DM and to provide an overview of its impact on QoL.https://www.mdpi.com/2673-4540/4/4/46female sexual dysfunctiontype 2 diabetes mellitusquality of life
spellingShingle Marija Rogoznica
Dražen Perica
Barbara Borovac
Andrej Belančić
Martina Matovinović
Sexual Dysfunction in Female Patients with Type 2 Diabetes Mellitus—Sneak Peek on an Important Quality of Life Determinant
Diabetology
female sexual dysfunction
type 2 diabetes mellitus
quality of life
title Sexual Dysfunction in Female Patients with Type 2 Diabetes Mellitus—Sneak Peek on an Important Quality of Life Determinant
title_full Sexual Dysfunction in Female Patients with Type 2 Diabetes Mellitus—Sneak Peek on an Important Quality of Life Determinant
title_fullStr Sexual Dysfunction in Female Patients with Type 2 Diabetes Mellitus—Sneak Peek on an Important Quality of Life Determinant
title_full_unstemmed Sexual Dysfunction in Female Patients with Type 2 Diabetes Mellitus—Sneak Peek on an Important Quality of Life Determinant
title_short Sexual Dysfunction in Female Patients with Type 2 Diabetes Mellitus—Sneak Peek on an Important Quality of Life Determinant
title_sort sexual dysfunction in female patients with type 2 diabetes mellitus sneak peek on an important quality of life determinant
topic female sexual dysfunction
type 2 diabetes mellitus
quality of life
url https://www.mdpi.com/2673-4540/4/4/46
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