Disulfiram induced reversible hypertension: A prospective case study and brief review
Disulfiram (DSF) is one of the recommended aids in the management of alcohol dependence. Hypertension may be a clinically significant, dose-dependent, and usually reversible adverse event of DSF therapy. We report 6 month prospective study of normotensive case of comorbid alcohol and tobacco depende...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2013-01-01
|
| Series: | Indian Journal of Psychological Medicine |
| Subjects: | |
| Online Access: | http://www.ijpm.info/article.asp?issn=0253-7176;year=2013;volume=35;issue=2;spage=217;epage=219;aulast=Kulkarni |
| _version_ | 1819125410792734720 |
|---|---|
| author | Ranganath R Kulkarni Bhavya K Bairy |
| author_facet | Ranganath R Kulkarni Bhavya K Bairy |
| author_sort | Ranganath R Kulkarni |
| collection | DOAJ |
| description | Disulfiram (DSF) is one of the recommended aids in the management of alcohol dependence. Hypertension may be a clinically significant, dose-dependent, and usually reversible adverse event of DSF therapy. We report 6 month prospective study of normotensive case of comorbid alcohol and tobacco dependence that developed reversible stage-II hypertension within 2-4 weeks of DSF therapy. We suggest that regular monitoring of blood pressure at least fortnightly for 1 st 3 months, followed by monthly for next 3 months, and later once in 3 months, may possibly detect "silent" adverse event of DSF - hypertension. |
| first_indexed | 2024-12-22T07:39:42Z |
| format | Article |
| id | doaj.art-b2f8c55ba347480eb40ccfe3469d59d4 |
| institution | Directory Open Access Journal |
| issn | 0253-7176 |
| language | English |
| last_indexed | 2024-12-22T07:39:42Z |
| publishDate | 2013-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Indian Journal of Psychological Medicine |
| spelling | doaj.art-b2f8c55ba347480eb40ccfe3469d59d42022-12-21T18:33:47ZengSAGE PublishingIndian Journal of Psychological Medicine0253-71762013-01-0135221721910.4103/0253-7176.116263Disulfiram induced reversible hypertension: A prospective case study and brief reviewRanganath R KulkarniBhavya K BairyDisulfiram (DSF) is one of the recommended aids in the management of alcohol dependence. Hypertension may be a clinically significant, dose-dependent, and usually reversible adverse event of DSF therapy. We report 6 month prospective study of normotensive case of comorbid alcohol and tobacco dependence that developed reversible stage-II hypertension within 2-4 weeks of DSF therapy. We suggest that regular monitoring of blood pressure at least fortnightly for 1 st 3 months, followed by monthly for next 3 months, and later once in 3 months, may possibly detect "silent" adverse event of DSF - hypertension.http://www.ijpm.info/article.asp?issn=0253-7176;year=2013;volume=35;issue=2;spage=217;epage=219;aulast=KulkarniAdverse eventalcohol dependencedisulfiramhypertension |
| spellingShingle | Ranganath R Kulkarni Bhavya K Bairy Disulfiram induced reversible hypertension: A prospective case study and brief review Indian Journal of Psychological Medicine Adverse event alcohol dependence disulfiram hypertension |
| title | Disulfiram induced reversible hypertension: A prospective case study and brief review |
| title_full | Disulfiram induced reversible hypertension: A prospective case study and brief review |
| title_fullStr | Disulfiram induced reversible hypertension: A prospective case study and brief review |
| title_full_unstemmed | Disulfiram induced reversible hypertension: A prospective case study and brief review |
| title_short | Disulfiram induced reversible hypertension: A prospective case study and brief review |
| title_sort | disulfiram induced reversible hypertension a prospective case study and brief review |
| topic | Adverse event alcohol dependence disulfiram hypertension |
| url | http://www.ijpm.info/article.asp?issn=0253-7176;year=2013;volume=35;issue=2;spage=217;epage=219;aulast=Kulkarni |
| work_keys_str_mv | AT ranganathrkulkarni disulfiraminducedreversiblehypertensionaprospectivecasestudyandbriefreview AT bhavyakbairy disulfiraminducedreversiblehypertensionaprospectivecasestudyandbriefreview |