Pharmacological agents targeting drug-tolerant persister cells in cancer

Current cancer therapy can be effective, but the development of drug resistant disease is the usual outcome. These drugs can eliminate most of the tumor burden but often fail to eliminate the rare, “Drug Tolerant Persister” (DTP) cell subpopulations in residual tumors, which can be referred to as “P...

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Bibliographic Details
Main Authors: Yu-Chi Chen, Krishne Gowda, Shantu Amin, Todd D. Schell, Arun K. Sharma, Gavin P. Robertson
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Pharmacological Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661824001075