Tacrolimus ointment in the management of atopic dermatitis
Antonello Baldo, Mariana Cafiero, Paola Di Caterino, Luisa Di CostanzoDepartment of Dermatology, University of Naples Federico II, Naples, ItalyAbstract: Atopic dermatitis (AD) is a chronic, relapsing, highly pruritic inflammatory skin disease. AD long-term treatment is usually required to control a...
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2009-01-01
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| Series: | Clinical, Cosmetic and Investigational Dermatology |
| Online Access: | http://www.dovepress.com/tacrolimus-ointment-in-the-management-of-atopic-dermatitis-a2824 |
| _version_ | 1830351246053081088 |
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| author | Antonello Baldo Mariana Cafiero Paola Di Caterino Luisa Di Costanzo |
| author_facet | Antonello Baldo Mariana Cafiero Paola Di Caterino Luisa Di Costanzo |
| author_sort | Antonello Baldo |
| collection | DOAJ |
| description | Antonello Baldo, Mariana Cafiero, Paola Di Caterino, Luisa Di CostanzoDepartment of Dermatology, University of Naples Federico II, Naples, ItalyAbstract: Atopic dermatitis (AD) is a chronic, relapsing, highly pruritic inflammatory skin disease. AD long-term treatment is usually required to control and prevent flares, and patients need a treatment that is safe and efficacious when applied continuously or intermittently over a prolonged period of time. The treatment options should be chosen according to age, clinical features and severity of the disease in every single patient. For the treatment of a chronic disease like AD, sustained tolerability and efficacy of the applied medications are essential. A topical immunomodulator, tacrolimus ointment, provides an alternative to topical corticosteroids without the associated adverse events. Tacrolimus is a macrolide lactone with unique immunomodulatory properties and strong anti-inflammatory activities and can be used without increasing the risk of infection or other non-application site adverse events, and without loss of effectiveness, in patients with AD.Keywords: atopic dermatitis, tacrolimus, safety |
| first_indexed | 2024-12-20T00:34:53Z |
| format | Article |
| id | doaj.art-b2ff57c9a0724d2eae4466c303efcd84 |
| institution | Directory Open Access Journal |
| issn | 1178-7015 |
| language | English |
| last_indexed | 2024-12-20T00:34:53Z |
| publishDate | 2009-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical, Cosmetic and Investigational Dermatology |
| spelling | doaj.art-b2ff57c9a0724d2eae4466c303efcd842022-12-21T19:59:48ZengDove Medical PressClinical, Cosmetic and Investigational Dermatology1178-70152009-01-012009default17Tacrolimus ointment in the management of atopic dermatitisAntonello BaldoMariana CafieroPaola Di CaterinoLuisa Di CostanzoAntonello Baldo, Mariana Cafiero, Paola Di Caterino, Luisa Di CostanzoDepartment of Dermatology, University of Naples Federico II, Naples, ItalyAbstract: Atopic dermatitis (AD) is a chronic, relapsing, highly pruritic inflammatory skin disease. AD long-term treatment is usually required to control and prevent flares, and patients need a treatment that is safe and efficacious when applied continuously or intermittently over a prolonged period of time. The treatment options should be chosen according to age, clinical features and severity of the disease in every single patient. For the treatment of a chronic disease like AD, sustained tolerability and efficacy of the applied medications are essential. A topical immunomodulator, tacrolimus ointment, provides an alternative to topical corticosteroids without the associated adverse events. Tacrolimus is a macrolide lactone with unique immunomodulatory properties and strong anti-inflammatory activities and can be used without increasing the risk of infection or other non-application site adverse events, and without loss of effectiveness, in patients with AD.Keywords: atopic dermatitis, tacrolimus, safetyhttp://www.dovepress.com/tacrolimus-ointment-in-the-management-of-atopic-dermatitis-a2824 |
| spellingShingle | Antonello Baldo Mariana Cafiero Paola Di Caterino Luisa Di Costanzo Tacrolimus ointment in the management of atopic dermatitis Clinical, Cosmetic and Investigational Dermatology |
| title | Tacrolimus ointment in the management of atopic dermatitis |
| title_full | Tacrolimus ointment in the management of atopic dermatitis |
| title_fullStr | Tacrolimus ointment in the management of atopic dermatitis |
| title_full_unstemmed | Tacrolimus ointment in the management of atopic dermatitis |
| title_short | Tacrolimus ointment in the management of atopic dermatitis |
| title_sort | tacrolimus ointment in the management of atopic dermatitis |
| url | http://www.dovepress.com/tacrolimus-ointment-in-the-management-of-atopic-dermatitis-a2824 |
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