How much (ATP) does it cost to build a trypanosome? A theoretical study on the quantity of ATP needed to maintain and duplicate a bloodstream-form Trypanosoma brucei cell.
ATP hydrolysis is required for the synthesis, transport and polymerization of monomers for macromolecules as well as for the assembly of the latter into cellular structures. Other cellular processes not directly related to synthesis of biomass, such as maintenance of membrane potential and cellular...
Main Authors: | Janaina F Nascimento, Rodolpho O O Souza, Mayke B Alencar, Sabrina Marsiccobetre, Ana M Murillo, Flávia S Damasceno, Richard B M M Girard, Letícia Marchese, Luis A Luévano-Martinez, Renan W Achjian, Jurgen R Haanstra, Paul A M Michels, Ariel M Silber |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-07-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1011522 |
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