Vitamin D levels assessment among the neonates with and without seizures: A single center cross-sectional study

Introduction: The impact that vitamin D (vit D) has on a variety of medical conditions like diabetes, cardiovascular, oncological, and central nervous system disorders has been a topic of interest for many years now. It is well-known that vit D deficiency is substantially more common in epileptics t...

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Main Authors: Nilamadhab Prusty, Sai Y Peela, Haifa Manaf, Smit Thakkar, Yaswanthi Yanamadala, Chapala Shashank
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2024;volume=16;issue=5;spage=293;epage=295;aulast=Prusty
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author Nilamadhab Prusty
Sai Y Peela
Haifa Manaf
Smit Thakkar
Yaswanthi Yanamadala
Chapala Shashank
author_facet Nilamadhab Prusty
Sai Y Peela
Haifa Manaf
Smit Thakkar
Yaswanthi Yanamadala
Chapala Shashank
author_sort Nilamadhab Prusty
collection DOAJ
description Introduction: The impact that vitamin D (vit D) has on a variety of medical conditions like diabetes, cardiovascular, oncological, and central nervous system disorders has been a topic of interest for many years now. It is well-known that vit D deficiency is substantially more common in epileptics than in healthy subjects. The current research was piloted to analyse the vit D levels of the blood in newborns with seizures, as well as mothers' vit D status included subjects. Materials and Methods: A cross-sectional examination was piloted at a tertiary care center, which had a neonatal intensive care unit (NICU). The subjects were neonates and their mothers. The levels of vit D were measured in term and late preterm newborns who had been brought to the NICU with convulsions. Term or late preterm infants who were healthy and hospitalized in the same hospital's postnatal unit as their mothers served as the controls for the study. Demographics, as well as the vit D levels of both the neonate and the mother, were estimated and compared and evaluated for any significance, keeping significance at less than 0.05. Results: Of the 72 neonates included, they were similarly distributed between the epileptic (37) and healthy subjects. (40) The mothersy subjects.cluded, they were sim D levels averaged 15.11 ded, they were similarly distributed b D levels of their newborns were 13.26 ± 5.12 ng/mL (P = 0.77). There was no significant variance between the healthy and epileptic neonates (P = 0.212). Conclusion: The current studyficant variance between the healthy and epileptic neonates (eptic with convulsions. Termserum vit D levels and epileptic activity in neonates. Nevertheless, the levels of the vitamin were < 20 ng/mL among all the neonates. Interventions to improve the vit D levels have to be implemented.
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spelling doaj.art-b30148acacf446b08932d0c7a88350d12024-04-04T16:37:39ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74062024-01-0116529329510.4103/jpbs.jpbs_497_23Vitamin D levels assessment among the neonates with and without seizures: A single center cross-sectional studyNilamadhab PrustySai Y PeelaHaifa ManafSmit ThakkarYaswanthi YanamadalaChapala ShashankIntroduction: The impact that vitamin D (vit D) has on a variety of medical conditions like diabetes, cardiovascular, oncological, and central nervous system disorders has been a topic of interest for many years now. It is well-known that vit D deficiency is substantially more common in epileptics than in healthy subjects. The current research was piloted to analyse the vit D levels of the blood in newborns with seizures, as well as mothers' vit D status included subjects. Materials and Methods: A cross-sectional examination was piloted at a tertiary care center, which had a neonatal intensive care unit (NICU). The subjects were neonates and their mothers. The levels of vit D were measured in term and late preterm newborns who had been brought to the NICU with convulsions. Term or late preterm infants who were healthy and hospitalized in the same hospital's postnatal unit as their mothers served as the controls for the study. Demographics, as well as the vit D levels of both the neonate and the mother, were estimated and compared and evaluated for any significance, keeping significance at less than 0.05. Results: Of the 72 neonates included, they were similarly distributed between the epileptic (37) and healthy subjects. (40) The mothersy subjects.cluded, they were sim D levels averaged 15.11 ded, they were similarly distributed b D levels of their newborns were 13.26 ± 5.12 ng/mL (P = 0.77). There was no significant variance between the healthy and epileptic neonates (P = 0.212). Conclusion: The current studyficant variance between the healthy and epileptic neonates (eptic with convulsions. Termserum vit D levels and epileptic activity in neonates. Nevertheless, the levels of the vitamin were < 20 ng/mL among all the neonates. Interventions to improve the vit D levels have to be implemented.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2024;volume=16;issue=5;spage=293;epage=295;aulast=Prustyhypocalcaemianeonatespediatricseizuresvitamin d
spellingShingle Nilamadhab Prusty
Sai Y Peela
Haifa Manaf
Smit Thakkar
Yaswanthi Yanamadala
Chapala Shashank
Vitamin D levels assessment among the neonates with and without seizures: A single center cross-sectional study
Journal of Pharmacy and Bioallied Sciences
hypocalcaemia
neonates
pediatric
seizures
vitamin d
title Vitamin D levels assessment among the neonates with and without seizures: A single center cross-sectional study
title_full Vitamin D levels assessment among the neonates with and without seizures: A single center cross-sectional study
title_fullStr Vitamin D levels assessment among the neonates with and without seizures: A single center cross-sectional study
title_full_unstemmed Vitamin D levels assessment among the neonates with and without seizures: A single center cross-sectional study
title_short Vitamin D levels assessment among the neonates with and without seizures: A single center cross-sectional study
title_sort vitamin d levels assessment among the neonates with and without seizures a single center cross sectional study
topic hypocalcaemia
neonates
pediatric
seizures
vitamin d
url http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2024;volume=16;issue=5;spage=293;epage=295;aulast=Prusty
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