Digital therapeutics in the clinic
Abstract Digital therapeutics are emerging as a new form of therapeutic interventions. Unlike conventional therapeutics, digital therapeutics deliver interventions directly to patients using an evidence‐based, clinically evaluated software to treat, manage, or prevent diseases. Digital therapeutics...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-07-01
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| Series: | Bioengineering & Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/btm2.10536 |
| _version_ | 1827898361323192320 |
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| author | Philana Phan Samir Mitragotri Zongmin Zhao |
| author_facet | Philana Phan Samir Mitragotri Zongmin Zhao |
| author_sort | Philana Phan |
| collection | DOAJ |
| description | Abstract Digital therapeutics are emerging as a new form of therapeutic interventions. Unlike conventional therapeutics, digital therapeutics deliver interventions directly to patients using an evidence‐based, clinically evaluated software to treat, manage, or prevent diseases. Digital therapeutics manifest in diverse forms such as web‐based applications, mobile applications on smart devices, virtual reality, and video games. As its own product category for FDA approval, digital therapeutics can function as stand‐alone treatments or in combination with conventional therapeutics to improve adherence and/or efficacy. Here, we review the clinical landscape of digital therapeutics. We summarize FDA‐approved products and their clinical use, overview >300 ongoing clinical trials, and discuss challenges for their clinical translation and strategies to overcome the same. |
| first_indexed | 2024-03-12T23:02:04Z |
| format | Article |
| id | doaj.art-b306d0fe57ff4f2f9b9027509fc63bb7 |
| institution | Directory Open Access Journal |
| issn | 2380-6761 |
| language | English |
| last_indexed | 2024-03-12T23:02:04Z |
| publishDate | 2023-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | Bioengineering & Translational Medicine |
| spelling | doaj.art-b306d0fe57ff4f2f9b9027509fc63bb72023-07-19T09:59:03ZengWileyBioengineering & Translational Medicine2380-67612023-07-0184n/an/a10.1002/btm2.10536Digital therapeutics in the clinicPhilana Phan0Samir Mitragotri1Zongmin Zhao2Department of Pharmaceutical Sciences, College of Pharmacy University of Illinois Chicago Chicago Illinois USAJohn A. Paulson School of Engineering and Applied Sciences Harvard University Cambridge Massachusetts USADepartment of Pharmaceutical Sciences, College of Pharmacy University of Illinois Chicago Chicago Illinois USAAbstract Digital therapeutics are emerging as a new form of therapeutic interventions. Unlike conventional therapeutics, digital therapeutics deliver interventions directly to patients using an evidence‐based, clinically evaluated software to treat, manage, or prevent diseases. Digital therapeutics manifest in diverse forms such as web‐based applications, mobile applications on smart devices, virtual reality, and video games. As its own product category for FDA approval, digital therapeutics can function as stand‐alone treatments or in combination with conventional therapeutics to improve adherence and/or efficacy. Here, we review the clinical landscape of digital therapeutics. We summarize FDA‐approved products and their clinical use, overview >300 ongoing clinical trials, and discuss challenges for their clinical translation and strategies to overcome the same.https://doi.org/10.1002/btm2.10536digiceuticalsdigital counselingdigital healthdigital medicinedigital technologydigital therapeutics |
| spellingShingle | Philana Phan Samir Mitragotri Zongmin Zhao Digital therapeutics in the clinic Bioengineering & Translational Medicine digiceuticals digital counseling digital health digital medicine digital technology digital therapeutics |
| title | Digital therapeutics in the clinic |
| title_full | Digital therapeutics in the clinic |
| title_fullStr | Digital therapeutics in the clinic |
| title_full_unstemmed | Digital therapeutics in the clinic |
| title_short | Digital therapeutics in the clinic |
| title_sort | digital therapeutics in the clinic |
| topic | digiceuticals digital counseling digital health digital medicine digital technology digital therapeutics |
| url | https://doi.org/10.1002/btm2.10536 |
| work_keys_str_mv | AT philanaphan digitaltherapeuticsintheclinic AT samirmitragotri digitaltherapeuticsintheclinic AT zongminzhao digitaltherapeuticsintheclinic |