Liver-stage fate determination in Plasmodium vivax parasites: Characterization of schizont growth and hypnozoite fating from patient isolates
Plasmodium vivax, one species of parasite causing human malaria, forms a dormant liver stage, termed the hypnozoite, which activate weeks, months or years after the primary infection, causing relapse episodes. Relapses significantly contribute to the vivax malaria burden and are only killed with dru...
Main Authors: | Amélie Vantaux, Julie Péneau, Caitlin A. Cooper, Dennis E. Kyle, Benoit Witkowski, Steven P. Maher |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-09-01
|
Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2022.976606/full |
Similar Items
-
Plasmodium vivax latent liver infection is characterized by persistent hypnozoites, hypnozoite-derived schizonts, and time-dependent efficacy of primaquine
by: Erika L. Flannery, et al.
Published: (2022-09-01) -
Ethiopian Plasmodium vivax hypnozoites formation dynamics and their susceptibility to reference antimalarial drugs
by: Laurent Dembele, et al.
Published: (2023-06-01) -
A recombinant antibody against Plasmodium vivax UIS4 for distinguishing replicating from dormant liver stages
by: Carola Schafer, et al.
Published: (2018-10-01) -
Population-level estimates of the proportion of Plasmodium vivax blood-stage infections attributable to relapses among febrile patients attending Adama Malaria Diagnostic Centre, East Shoa Zone, Oromia, Ethiopia
by: Lemu Golassa, et al.
Published: (2017-07-01) -
Vivax malaria: a possible stumbling block for malaria elimination in India
by: Ashwani Kumar, et al.
Published: (2024-01-01)