DISTRIBUTION OF GLEASON SCO¬RE IN PROSTATE ZONES AMONG PROSTATIC CANCER PATIENTS
Objective: To analyze the distribution features of Gleason score in the different prostate zones. Material & Method: Twenty paraffin block specimens of radical prostatectomy were analyzed looking for Gleason score distribution in each zone. Specimens were stained with Hematoxilin Eosin. Results:...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
IKATAN AHLI UROLOGI INDONESIA
2014-11-01
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| Series: | Jurnal Urologi Indonesia |
| Online Access: | https://juri.urologi.or.id/juri/article/view/50 |
| _version_ | 1798031491591045120 |
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| author | Indra Jaya Suwandi Sugandi Anglita Yantisetiasti Betthy S. S. Hernowo |
| author_facet | Indra Jaya Suwandi Sugandi Anglita Yantisetiasti Betthy S. S. Hernowo |
| author_sort | Indra Jaya |
| collection | DOAJ |
| description | Objective: To analyze the distribution features of Gleason score in the different prostate zones. Material & Method: Twenty paraffin block specimens of radical prostatectomy were analyzed looking for Gleason score distribution in each zone. Specimens were stained with Hematoxilin Eosin. Results: Among the 20 cancers, 16 (80%) specimens had more than one focus. Most foci were found in peripheral zone (95%), only one specimen contained foci solely found in transitional zone. More than half (55%) prostate specimens contain three different Gleason grades. Only one specimen contained a single grade. Conclusion: Our results confirm the heterogeneous, multifocal, and multizonal nature of prostate carcinomas. Most specimens had more than one tumor focus, with predominant location in the peripheral zone. Almost all transition zone foci were found concomitantly with peripheral zone foci.
Keywords: Prostate cancer, prostate zones, Gleason score. |
| first_indexed | 2024-04-11T19:58:24Z |
| format | Article |
| id | doaj.art-b30aceb127344dad93aa84d956372296 |
| institution | Directory Open Access Journal |
| issn | 0853-442X 2355-1402 |
| language | English |
| last_indexed | 2024-04-11T19:58:24Z |
| publishDate | 2014-11-01 |
| publisher | IKATAN AHLI UROLOGI INDONESIA |
| record_format | Article |
| series | Jurnal Urologi Indonesia |
| spelling | doaj.art-b30aceb127344dad93aa84d9563722962022-12-22T04:05:50ZengIKATAN AHLI UROLOGI INDONESIAJurnal Urologi Indonesia0853-442X2355-14022014-11-0119110.32421/juri.v19i1.5050DISTRIBUTION OF GLEASON SCO¬RE IN PROSTATE ZONES AMONG PROSTATIC CANCER PATIENTSIndra Jaya0Suwandi Sugandi1Anglita Yantisetiasti2Betthy S. S. Hernowo3Department of Urology, Faculty of Medicine/Padjadjaran University, Hasan Sadikin Hospital, BandungDepartment of Urology, Faculty of Medicine/Padjadjaran University, Hasan Sadikin Hospital, BandungDepartment of Pathology, Faculty of Medicine/Padjadjaran University, Hasan Sadikin Hospital, Bandung.Department of Pathology, Faculty of Medicine/Padjadjaran University, Hasan Sadikin Hospital, Bandung.Objective: To analyze the distribution features of Gleason score in the different prostate zones. Material & Method: Twenty paraffin block specimens of radical prostatectomy were analyzed looking for Gleason score distribution in each zone. Specimens were stained with Hematoxilin Eosin. Results: Among the 20 cancers, 16 (80%) specimens had more than one focus. Most foci were found in peripheral zone (95%), only one specimen contained foci solely found in transitional zone. More than half (55%) prostate specimens contain three different Gleason grades. Only one specimen contained a single grade. Conclusion: Our results confirm the heterogeneous, multifocal, and multizonal nature of prostate carcinomas. Most specimens had more than one tumor focus, with predominant location in the peripheral zone. Almost all transition zone foci were found concomitantly with peripheral zone foci. Keywords: Prostate cancer, prostate zones, Gleason score.https://juri.urologi.or.id/juri/article/view/50 |
| spellingShingle | Indra Jaya Suwandi Sugandi Anglita Yantisetiasti Betthy S. S. Hernowo DISTRIBUTION OF GLEASON SCO¬RE IN PROSTATE ZONES AMONG PROSTATIC CANCER PATIENTS Jurnal Urologi Indonesia |
| title | DISTRIBUTION OF GLEASON SCO¬RE IN PROSTATE ZONES AMONG PROSTATIC CANCER PATIENTS |
| title_full | DISTRIBUTION OF GLEASON SCO¬RE IN PROSTATE ZONES AMONG PROSTATIC CANCER PATIENTS |
| title_fullStr | DISTRIBUTION OF GLEASON SCO¬RE IN PROSTATE ZONES AMONG PROSTATIC CANCER PATIENTS |
| title_full_unstemmed | DISTRIBUTION OF GLEASON SCO¬RE IN PROSTATE ZONES AMONG PROSTATIC CANCER PATIENTS |
| title_short | DISTRIBUTION OF GLEASON SCO¬RE IN PROSTATE ZONES AMONG PROSTATIC CANCER PATIENTS |
| title_sort | distribution of gleason sco¬re in prostate zones among prostatic cancer patients |
| url | https://juri.urologi.or.id/juri/article/view/50 |
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