HBV - infection in children with perinatal infection. Clinical report of familial hepatitis B
Hepatitis B, despite of being a controlled infection today, is one of the most common form of hepatitis in the world. According to the experts' evaluation there are about 3 million patients with chronic hepatitis B in our country. The global strategy of the World Health Organization includes th...
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2021-10-01
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| Series: | Журнал инфектологии |
| Subjects: | |
| Online Access: | https://journal.niidi.ru/jofin/article/view/1248 |
| _version_ | 1797702648694046720 |
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| author | I. V. Shilova Yu. V. Ostankova L. G. Goryacheva A. V. Semenov |
| author_facet | I. V. Shilova Yu. V. Ostankova L. G. Goryacheva A. V. Semenov |
| author_sort | I. V. Shilova |
| collection | DOAJ |
| description | Hepatitis B, despite of being a controlled infection today, is one of the most common form of hepatitis in the world. According to the experts' evaluation there are about 3 million patients with chronic hepatitis B in our country. The global strategy of the World Health Organization includes the elimination of viral hepatitis by 2030.The program used in the North-West Federal District to eliminate acute hepatitis B has reduced the incidence rate due to the widespread vaccination coverage of children and the annual increase in adult immunization coverage.However, the relevance of HBV-infection in children still remains high which is associated with a high infection by hepatitis B virus in women of childbearing age and the possibility of the transmission of the infection from mother to her child. In case of perinatal infection the formation of chronic hepatitis B in children reaches up to 90%. The natural course of chronic hepatitis B is characterized by a change in pathogenetically determined phases, and HBsAg-negative infection, which is a latent (occult) form of hepatitis, was added to them in 2009. Occult hepatitis B is an epidemiological danger, for the child as well, if the mother suffers from this form of chronic hepatitis B. Monitoring of pregnant women is often limited to identifying only HBsAg, which is not enough to detect occult hepatitis B. Lately diagnosed occult HBV-infection can become a source of the infection for the baby, especially in cases when due to some reasons there are disorders in hepatitis B vaccination schedule after birth. The article presents an interesting clinical case of family hepatitis B. |
| first_indexed | 2024-03-12T04:53:07Z |
| format | Article |
| id | doaj.art-b30b5e060700482499b004f92788272a |
| institution | Directory Open Access Journal |
| issn | 2072-6732 |
| language | Russian |
| last_indexed | 2024-03-12T04:53:07Z |
| publishDate | 2021-10-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj.art-b30b5e060700482499b004f92788272a2023-09-03T09:18:31ZrusJournal InfectologyЖурнал инфектологии2072-67322021-10-0113312012410.22625/2072-6732-2021-13-3-120-124942HBV - infection in children with perinatal infection. Clinical report of familial hepatitis BI. V. Shilova0Yu. V. Ostankova1L. G. Goryacheva2A. V. Semenov3Детский научно-клинический центр инфекционных болезнейСанкт-Петербургский научно-исследовательский институт эпидемиологии и микробиологии им. ПастераДетский научно-клинический центр инфекционных болезней; Санкт-Петербургский государственный педиатрический медицинский университетСанкт-Петербургский научно-исследовательский институт эпидемиологии и микробиологии им. Пастера; Северо-Западный государственный медицинский университет им. И.И. МечниковаHepatitis B, despite of being a controlled infection today, is one of the most common form of hepatitis in the world. According to the experts' evaluation there are about 3 million patients with chronic hepatitis B in our country. The global strategy of the World Health Organization includes the elimination of viral hepatitis by 2030.The program used in the North-West Federal District to eliminate acute hepatitis B has reduced the incidence rate due to the widespread vaccination coverage of children and the annual increase in adult immunization coverage.However, the relevance of HBV-infection in children still remains high which is associated with a high infection by hepatitis B virus in women of childbearing age and the possibility of the transmission of the infection from mother to her child. In case of perinatal infection the formation of chronic hepatitis B in children reaches up to 90%. The natural course of chronic hepatitis B is characterized by a change in pathogenetically determined phases, and HBsAg-negative infection, which is a latent (occult) form of hepatitis, was added to them in 2009. Occult hepatitis B is an epidemiological danger, for the child as well, if the mother suffers from this form of chronic hepatitis B. Monitoring of pregnant women is often limited to identifying only HBsAg, which is not enough to detect occult hepatitis B. Lately diagnosed occult HBV-infection can become a source of the infection for the baby, especially in cases when due to some reasons there are disorders in hepatitis B vaccination schedule after birth. The article presents an interesting clinical case of family hepatitis B.https://journal.niidi.ru/jofin/article/view/1248детиhbv-инфекцияперинатальное инфицированиеоккультный гепатит в |
| spellingShingle | I. V. Shilova Yu. V. Ostankova L. G. Goryacheva A. V. Semenov HBV - infection in children with perinatal infection. Clinical report of familial hepatitis B Журнал инфектологии дети hbv-инфекция перинатальное инфицирование оккультный гепатит в |
| title | HBV - infection in children with perinatal infection. Clinical report of familial hepatitis B |
| title_full | HBV - infection in children with perinatal infection. Clinical report of familial hepatitis B |
| title_fullStr | HBV - infection in children with perinatal infection. Clinical report of familial hepatitis B |
| title_full_unstemmed | HBV - infection in children with perinatal infection. Clinical report of familial hepatitis B |
| title_short | HBV - infection in children with perinatal infection. Clinical report of familial hepatitis B |
| title_sort | hbv infection in children with perinatal infection clinical report of familial hepatitis b |
| topic | дети hbv-инфекция перинатальное инфицирование оккультный гепатит в |
| url | https://journal.niidi.ru/jofin/article/view/1248 |
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