Molecular determinants of large cargo transport into the nucleus

Molecular determinants of large cargo transport into the nucleus

Nucleocytoplasmic transport is tightly regulated by the nuclear pore complex (NPC). Among the thousands of molecules that cross the NPC, even very large (>15 nm) cargoes such as pathogens, mRNAs and pre-ribosomes can pass the NPC intact. For these cargoes, there is little quantitative underst...

Celý popis

Podrobná bibliografie
Hlavní autoři: Giulia Paci, Tiantian Zheng, Joana Caria, Anton Zilman, Edward A Lemke
Médium: Článek
Jazyk:English
Vydáno: eLife Sciences Publications Ltd 2020-07-01
Edice:eLife
Témata:
nuclear transport
permeabilized cells
large cargo
import kinetics
NLS
capsid
On-line přístup:https://elifesciences.org/articles/55963

Internet

https://elifesciences.org/articles/55963

Podobné jednotky