Molecular determinants of large cargo transport into the nucleus

Nucleocytoplasmic transport is tightly regulated by the nuclear pore complex (NPC). Among the thousands of molecules that cross the NPC, even very large (>15 nm) cargoes such as pathogens, mRNAs and pre-ribosomes can pass the NPC intact. For these cargoes, there is little quantitative underst...

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Détails bibliographiques
Auteurs principaux: Giulia Paci, Tiantian Zheng, Joana Caria, Anton Zilman, Edward A Lemke
Format: Article
Langue:English
Publié: eLife Sciences Publications Ltd 2020-07-01
Collection:eLife
Sujets:
Accès en ligne:https://elifesciences.org/articles/55963