Molecular determinants of large cargo transport into the nucleus

Nucleocytoplasmic transport is tightly regulated by the nuclear pore complex (NPC). Among the thousands of molecules that cross the NPC, even very large (>15 nm) cargoes such as pathogens, mRNAs and pre-ribosomes can pass the NPC intact. For these cargoes, there is little quantitative underst...

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Những tác giả chính: Giulia Paci, Tiantian Zheng, Joana Caria, Anton Zilman, Edward A Lemke
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: eLife Sciences Publications Ltd 2020-07-01
Loạt:eLife
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Truy cập trực tuyến:https://elifesciences.org/articles/55963