A facile and efficient synthesis of 1,8-dioxodecahydroacridines derivatives catalyzed by cobalt–alanine metal complex under aqueous ethanol media
Abstract A facile and convenient method for the synthesis of acridines and its derivatives was developed through one-pot, three-component condensation reaction of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexanedione, aryl amines or ammonium acetates in the presence of a catalytic amount of cobalt–a...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2019-03-01
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| Series: | BMC Chemistry |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13065-019-0545-3 |
| _version_ | 1818012943622602752 |
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| author | M. Mujahid Alam Ahmed T. Mubarak Mohammed A. Assiri S. Merajuddin Ahmed Ahmed M. Fouda |
| author_facet | M. Mujahid Alam Ahmed T. Mubarak Mohammed A. Assiri S. Merajuddin Ahmed Ahmed M. Fouda |
| author_sort | M. Mujahid Alam |
| collection | DOAJ |
| description | Abstract A facile and convenient method for the synthesis of acridines and its derivatives was developed through one-pot, three-component condensation reaction of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexanedione, aryl amines or ammonium acetates in the presence of a catalytic amount of cobalt–alanine metal complex using aqueous ethanol as a reaction medium is reported. The present described novel methodology offers several advantages over the traditional methods reported in the literature, such as mild reaction conditions, inexpensive catalyst, short reaction times, excellent yields of products, simplicity and easy workup are the advantages of this procedure. |
| first_indexed | 2024-04-14T06:26:23Z |
| format | Article |
| id | doaj.art-b30e153828344268a3251c86152234ee |
| institution | Directory Open Access Journal |
| issn | 2661-801X |
| language | English |
| last_indexed | 2024-04-14T06:26:23Z |
| publishDate | 2019-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Chemistry |
| spelling | doaj.art-b30e153828344268a3251c86152234ee2022-12-22T02:07:47ZengBMCBMC Chemistry2661-801X2019-03-0113111010.1186/s13065-019-0545-3A facile and efficient synthesis of 1,8-dioxodecahydroacridines derivatives catalyzed by cobalt–alanine metal complex under aqueous ethanol mediaM. Mujahid Alam0Ahmed T. Mubarak1Mohammed A. Assiri2S. Merajuddin Ahmed3Ahmed M. Fouda4Department of Chemistry, King Khalid UniversityDepartment of Chemistry, King Khalid UniversityDepartment of Chemistry, King Khalid UniversityDepartment of Chemistry, King Khalid UniversityDepartment of Chemistry, King Khalid UniversityAbstract A facile and convenient method for the synthesis of acridines and its derivatives was developed through one-pot, three-component condensation reaction of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexanedione, aryl amines or ammonium acetates in the presence of a catalytic amount of cobalt–alanine metal complex using aqueous ethanol as a reaction medium is reported. The present described novel methodology offers several advantages over the traditional methods reported in the literature, such as mild reaction conditions, inexpensive catalyst, short reaction times, excellent yields of products, simplicity and easy workup are the advantages of this procedure.http://link.springer.com/article/10.1186/s13065-019-0545-3Cobalt–alanine metal complexMulti component reaction (MCR)DimedoneAmmonium acetate1,8-DioxodecahydroacridineOne-pot synthesis |
| spellingShingle | M. Mujahid Alam Ahmed T. Mubarak Mohammed A. Assiri S. Merajuddin Ahmed Ahmed M. Fouda A facile and efficient synthesis of 1,8-dioxodecahydroacridines derivatives catalyzed by cobalt–alanine metal complex under aqueous ethanol media BMC Chemistry Cobalt–alanine metal complex Multi component reaction (MCR) Dimedone Ammonium acetate 1,8-Dioxodecahydroacridine One-pot synthesis |
| title | A facile and efficient synthesis of 1,8-dioxodecahydroacridines derivatives catalyzed by cobalt–alanine metal complex under aqueous ethanol media |
| title_full | A facile and efficient synthesis of 1,8-dioxodecahydroacridines derivatives catalyzed by cobalt–alanine metal complex under aqueous ethanol media |
| title_fullStr | A facile and efficient synthesis of 1,8-dioxodecahydroacridines derivatives catalyzed by cobalt–alanine metal complex under aqueous ethanol media |
| title_full_unstemmed | A facile and efficient synthesis of 1,8-dioxodecahydroacridines derivatives catalyzed by cobalt–alanine metal complex under aqueous ethanol media |
| title_short | A facile and efficient synthesis of 1,8-dioxodecahydroacridines derivatives catalyzed by cobalt–alanine metal complex under aqueous ethanol media |
| title_sort | facile and efficient synthesis of 1 8 dioxodecahydroacridines derivatives catalyzed by cobalt alanine metal complex under aqueous ethanol media |
| topic | Cobalt–alanine metal complex Multi component reaction (MCR) Dimedone Ammonium acetate 1,8-Dioxodecahydroacridine One-pot synthesis |
| url | http://link.springer.com/article/10.1186/s13065-019-0545-3 |
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