Prevalence and risk factors of delirium in psychiatric patients with critical illness
Purpose: Delirium is a serious neuropsychiatric syndrome, which can lead to poor outcomes, especially among patients with critical illness, but is easily missed among psychiatric patients. Some delirium-associated risks have been confirmed for critical patients and psychiatric patients. Nevertheless...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | Psychiatry Research Communications |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772598723000077 |
| _version_ | 1797810588608364544 |
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| author | Lina Ren Yongjun Wang |
| author_facet | Lina Ren Yongjun Wang |
| author_sort | Lina Ren |
| collection | DOAJ |
| description | Purpose: Delirium is a serious neuropsychiatric syndrome, which can lead to poor outcomes, especially among patients with critical illness, but is easily missed among psychiatric patients. Some delirium-associated risks have been confirmed for critical patients and psychiatric patients. Nevertheless, the research about delirium in psychiatric patients with critical illness is rare. Methods: This study aims to investigate the prevalence and risk factors of delirium in psychiatric patients with critical illness. We assessed 425 patients diagnosed with critical illness from Shenzhen Kangning hospital from January 1, 2019, to December 31, 2021, and registered their demographic information, medical history and comorbidities. Patients underwent a psychiatric examination using the Confusion Assessment Method (CAM). Results: Among the 425 critical illness inpatients, 143 had delirium (prevalence of 33.6%). The most common associations were infectious disease (46.9%), electrolyte disturbance (48.3%), cerebrovascular disease (39.9%), and liver or kidney dysfunction (26.6%). The married status (OR = 3.450, p < 0.001), infectious diseases (OR = 2.862, p < 0.001), electrolyte disturbances (OR = 1.991, p = 0.009) and the organic mental disorder (OR = 5.611, p < 0.001) were independent non-modifiable factors associated with an increased risk of delirium. Conclusions: According to the study results, the delirium prevalence was about 33%. The organic mental disorder, infectious disease, electrolyte disturbance, cerebrovascular disease, and liver or kidney dysfunction were the risk factors for delirium in psychiatric patients with critical illness. Unexpectedly, the use of olanzapine or haloperidol showed no relevance to delirium. |
| first_indexed | 2024-03-13T07:11:08Z |
| format | Article |
| id | doaj.art-b30f3bc7fafb47aeb074ca1b10dfed1e |
| institution | Directory Open Access Journal |
| issn | 2772-5987 |
| language | English |
| last_indexed | 2024-03-13T07:11:08Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Psychiatry Research Communications |
| spelling | doaj.art-b30f3bc7fafb47aeb074ca1b10dfed1e2023-06-06T04:00:58ZengElsevierPsychiatry Research Communications2772-59872023-06-0132100108Prevalence and risk factors of delirium in psychiatric patients with critical illnessLina Ren0Yongjun Wang1Shenzhen Mental Health Centre, Shenzhen Kangning Hospital, Shenzhen, 518118, ChinaCorresponding author. Shenzhen Mental Health Centre, Shenzhen Kangning Hospital, 77#, ZhenBi Rd, Pingshan District, Shenzhen, 518118, China.; Shenzhen Mental Health Centre, Shenzhen Kangning Hospital, Shenzhen, 518118, ChinaPurpose: Delirium is a serious neuropsychiatric syndrome, which can lead to poor outcomes, especially among patients with critical illness, but is easily missed among psychiatric patients. Some delirium-associated risks have been confirmed for critical patients and psychiatric patients. Nevertheless, the research about delirium in psychiatric patients with critical illness is rare. Methods: This study aims to investigate the prevalence and risk factors of delirium in psychiatric patients with critical illness. We assessed 425 patients diagnosed with critical illness from Shenzhen Kangning hospital from January 1, 2019, to December 31, 2021, and registered their demographic information, medical history and comorbidities. Patients underwent a psychiatric examination using the Confusion Assessment Method (CAM). Results: Among the 425 critical illness inpatients, 143 had delirium (prevalence of 33.6%). The most common associations were infectious disease (46.9%), electrolyte disturbance (48.3%), cerebrovascular disease (39.9%), and liver or kidney dysfunction (26.6%). The married status (OR = 3.450, p < 0.001), infectious diseases (OR = 2.862, p < 0.001), electrolyte disturbances (OR = 1.991, p = 0.009) and the organic mental disorder (OR = 5.611, p < 0.001) were independent non-modifiable factors associated with an increased risk of delirium. Conclusions: According to the study results, the delirium prevalence was about 33%. The organic mental disorder, infectious disease, electrolyte disturbance, cerebrovascular disease, and liver or kidney dysfunction were the risk factors for delirium in psychiatric patients with critical illness. Unexpectedly, the use of olanzapine or haloperidol showed no relevance to delirium.http://www.sciencedirect.com/science/article/pii/S2772598723000077DeliriumPsychiatryAntipsychotic drugPrevalenceRisk factors |
| spellingShingle | Lina Ren Yongjun Wang Prevalence and risk factors of delirium in psychiatric patients with critical illness Psychiatry Research Communications Delirium Psychiatry Antipsychotic drug Prevalence Risk factors |
| title | Prevalence and risk factors of delirium in psychiatric patients with critical illness |
| title_full | Prevalence and risk factors of delirium in psychiatric patients with critical illness |
| title_fullStr | Prevalence and risk factors of delirium in psychiatric patients with critical illness |
| title_full_unstemmed | Prevalence and risk factors of delirium in psychiatric patients with critical illness |
| title_short | Prevalence and risk factors of delirium in psychiatric patients with critical illness |
| title_sort | prevalence and risk factors of delirium in psychiatric patients with critical illness |
| topic | Delirium Psychiatry Antipsychotic drug Prevalence Risk factors |
| url | http://www.sciencedirect.com/science/article/pii/S2772598723000077 |
| work_keys_str_mv | AT linaren prevalenceandriskfactorsofdeliriuminpsychiatricpatientswithcriticalillness AT yongjunwang prevalenceandriskfactorsofdeliriuminpsychiatricpatientswithcriticalillness |