HOTAIR: a potential metastatic, drug-resistant and prognostic regulator of breast cancer

HOTAIR: a potential metastatic, drug-resistant and prognostic regulator of breast cancer

Abstract HOX transcript antisense intergenic RNA (HOTAIR) is an oncogenic non-coding RNA whose expression is strongly correlated with the tumor grade and prognosis of a variety of carcinomas including breast cancer (BC). HOTAIR regulates various target genes via sponging and epigenetic mechanisms an...

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Main Authors: Ganji Seeta Rama Raju, Eluri Pavitra, Sai Samyuktha Bandaru, Ganji Lakshmi Varaprasad, Ganji Purnachandra Nagaraju, Rama Rao Malla, Yun Suk Huh, Young-Kyu Han
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Molecular Cancer
Subjects:
Breast cancer
Drug resistance
HOTAIR
Metastasis
Prognosis
Online Access:https://doi.org/10.1186/s12943-023-01765-3

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