Antifibrotic Mechanism of Pinocembrin: Impact on Oxidative Stress, Inflammation and TGF-β /Smad Inhibition in Rats
Introduction. The present study aimed to elucidate the potential antifibrotic effects of pinocembrin (PIN), a flavanone found abundantly in honey and propolis, by studying its effect on different oxidative stress, inflammatory and fibrosis markers in an experimental model of CCl4-induced liver fibro...
Main Authors: | Marwa M. Said, Samar S. Azab, Noha M. Saeed, Ebtehal El-Demerdash |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-03-01
|
Series: | Annals of Hepatology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1665268119301632 |
Similar Items
-
Pinocembrin ameliorates post-infarct heart failure through activation of Nrf2/HO-1 signaling pathway
by: Xiuhuan Chen, et al.
Published: (2021-09-01) -
Pinocembrin Ameliorates Skin Fibrosis via Inhibiting TGF-β1 Signaling Pathway
by: Xiaohe Li, et al.
Published: (2021-08-01) -
Regulation of ATP levels in Escherichia coli using CRISPR interference for enhanced pinocembrin production
by: Sha Tao, et al.
Published: (2018-09-01) -
Stilbene glycoside protects osteoblasts against oxidative damage via Nrf2/HO-1 and NF-κB signaling pathways
by: Jian Cheng, et al.
Published: (2018-12-01) -
Pinocembrin Protects the Brain against Ischemia-Reperfusion Injury and Reverses the Autophagy Dysfunction in the Penumbra Area
by: Gang Zhao, et al.
Published: (2014-09-01)