Modeling subcortical ischemic white matter injury in rodents: unmet need for a breakthrough in translational research

Modeling subcortical ischemic white matter injury in rodents: unmet need for a breakthrough in translational research

Subcortical ischemic white matter injury (SIWMI), pathological correlate of white matter hyperintensities or leukoaraiosis on magnetic resonance imaging, is a common cause of cognitive decline in elderly. Despite its high prevalence, it remains unknown how various components of the white matter dege...

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Bibliographic Details
Main Authors: Yuexian Cui, Xuelian Jin, Jun Young Choi, Byung Gon Kim
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
animal model; axonal degeneration; demyelination; hypertension; ischemia; oligodendrocytes; subcortical ischemic white matter injury; vascular cognitive impairment; white matter hyperintensities
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=4;spage=638;epage=642;aulast=Cui

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