Liver Tissue Regeneration using Nano Silver impregnated Sodium Alginate/PVA Composite Nanofibres
Liver regeneration is a highly organized tissue regrowth process and is the most important reaction of the injured liver. The present study endeavors towards the preparation and characterization of nanoporous Sodium Alginate (SA)/ Poly Vinyl Alcohol (PVA) composite, nanofibrous scaffolds coated with...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Ital Publication
2020-03-01
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| Series: | SciMedicine Journal |
| Subjects: | |
| Online Access: | https://scimedjournal.org/index.php/SMJ/article/view/56 |
| _version_ | 1818997405845028864 |
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| author | Manikandan G Yuvashree M Sangeetha A Bhuvana K P Sanjay K Nayak |
| author_facet | Manikandan G Yuvashree M Sangeetha A Bhuvana K P Sanjay K Nayak |
| author_sort | Manikandan G |
| collection | DOAJ |
| description | Liver regeneration is a highly organized tissue regrowth process and is the most important reaction of the injured liver. The present study endeavors towards the preparation and characterization of nanoporous Sodium Alginate (SA)/ Poly Vinyl Alcohol (PVA) composite, nanofibrous scaffolds coated with silver (Ag) nanoparticles for hepatocellular regeneration. Chitosan based Silver nanoparticles possess high antibacterial activity has been preferred in the scaffold preparation to improve the antibacterial properties. The structural characterization of Ag Nanoparticles revealed the amorphous nature with an average particle size of 300 nm. Nanofibres (Scaffolds) were prepared by electrospinning SA/PVA solution at a voltage of 18-25 kV and Ag NPs were coated on it for antibacterial activity. Invitro studies denoted the growth of nitro compounds, amides and collagen which are the major constituents of liver tissue. |
| first_indexed | 2024-12-20T21:45:07Z |
| format | Article |
| id | doaj.art-b3200049b79d44f5a7f1802abb5655ad |
| institution | Directory Open Access Journal |
| issn | 2704-9833 |
| language | English |
| last_indexed | 2024-12-20T21:45:07Z |
| publishDate | 2020-03-01 |
| publisher | Ital Publication |
| record_format | Article |
| series | SciMedicine Journal |
| spelling | doaj.art-b3200049b79d44f5a7f1802abb5655ad2022-12-21T19:25:42ZengItal PublicationSciMedicine Journal2704-98332020-03-0121162110.28991/SciMedJ-2020-0201-323Liver Tissue Regeneration using Nano Silver impregnated Sodium Alginate/PVA Composite NanofibresManikandan G0Yuvashree M1Sangeetha A2Bhuvana K P3Sanjay K Nayak4Department of Plastics Technology, Central Institute of Plastics Engineering & Technology (CIPET: IPT), Chennai,Department of Plastics Technology, Central Institute of Plastics Engineering & Technology (CIPET: IPT), Chennai,CIPET: School for Advanced Research in Polymers (SARP) - ARSTPS, Chennai,Department of Plastics Technology, Central Institute of Plastics Engineering & Technology (CIPET: IPT), Chennai,CIPET: School for Advanced Research in Polymers (SARP) - ARSTPS, Chennai,Liver regeneration is a highly organized tissue regrowth process and is the most important reaction of the injured liver. The present study endeavors towards the preparation and characterization of nanoporous Sodium Alginate (SA)/ Poly Vinyl Alcohol (PVA) composite, nanofibrous scaffolds coated with silver (Ag) nanoparticles for hepatocellular regeneration. Chitosan based Silver nanoparticles possess high antibacterial activity has been preferred in the scaffold preparation to improve the antibacterial properties. The structural characterization of Ag Nanoparticles revealed the amorphous nature with an average particle size of 300 nm. Nanofibres (Scaffolds) were prepared by electrospinning SA/PVA solution at a voltage of 18-25 kV and Ag NPs were coated on it for antibacterial activity. Invitro studies denoted the growth of nitro compounds, amides and collagen which are the major constituents of liver tissue.https://scimedjournal.org/index.php/SMJ/article/view/56chitosan based silver nanoparticleselectrospinningsodium alginateliver tissue regeneration and antibacterial activity. |
| spellingShingle | Manikandan G Yuvashree M Sangeetha A Bhuvana K P Sanjay K Nayak Liver Tissue Regeneration using Nano Silver impregnated Sodium Alginate/PVA Composite Nanofibres SciMedicine Journal chitosan based silver nanoparticles electrospinning sodium alginate liver tissue regeneration and antibacterial activity. |
| title | Liver Tissue Regeneration using Nano Silver impregnated Sodium Alginate/PVA Composite Nanofibres |
| title_full | Liver Tissue Regeneration using Nano Silver impregnated Sodium Alginate/PVA Composite Nanofibres |
| title_fullStr | Liver Tissue Regeneration using Nano Silver impregnated Sodium Alginate/PVA Composite Nanofibres |
| title_full_unstemmed | Liver Tissue Regeneration using Nano Silver impregnated Sodium Alginate/PVA Composite Nanofibres |
| title_short | Liver Tissue Regeneration using Nano Silver impregnated Sodium Alginate/PVA Composite Nanofibres |
| title_sort | liver tissue regeneration using nano silver impregnated sodium alginate pva composite nanofibres |
| topic | chitosan based silver nanoparticles electrospinning sodium alginate liver tissue regeneration and antibacterial activity. |
| url | https://scimedjournal.org/index.php/SMJ/article/view/56 |
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