Tremorgenic mycotoxicosis in cattle, caused by Claviceps paspali
Claviceps paspali is a fungus that mainly parasitises Paspalum dilatatum, generating a structure denominated sclerotium, in which indole-diterpenoid alkaloids are isolated. Its action mechanism is related to the inhibition of the gamma-aminobutyric acid receptor. It basically affects bovines, trigge...
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| Format: | Article |
| Language: | English |
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Czech Academy of Agricultural Sciences
2023-01-01
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| Series: | Veterinární Medicína |
| Subjects: | |
| Online Access: | https://vetmed.agriculturejournals.cz/artkey/vet-202212-0005_tremorgenic-mycotoxicosis-in-cattle-caused-by-claviceps-paspali.php |
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| author | N Ayala-Soldado Lora-Benitez AJ R Mora-Medina Molina-Lopez AMª Artillo-Guimera JI Moyano-Salvago MªR |
| author_facet | N Ayala-Soldado Lora-Benitez AJ R Mora-Medina Molina-Lopez AMª Artillo-Guimera JI Moyano-Salvago MªR |
| author_sort | N Ayala-Soldado |
| collection | DOAJ |
| description | Claviceps paspali is a fungus that mainly parasitises Paspalum dilatatum, generating a structure denominated sclerotium, in which indole-diterpenoid alkaloids are isolated. Its action mechanism is related to the inhibition of the gamma-aminobutyric acid receptor. It basically affects bovines, triggering the tremorgenic syndrome, the prevalence of this intoxication being relatively low in Europe. This work describes a clinical case on a cattle farm in Seville (southern Spain), composed of 91 bovines, 60% of which were principally affected with nervous clinical signs. The diagnosis was based on a clinical inspection of the animals, as well as of the presence of paspalum seed heads containing the sclerotia of Claviceps paspali in the plants present in the pastures. The causal agent was identified as being Claviceps paspali, which had parasitised numerous examples of Paspalum paspaloides. The indole-diterpenoid alkaloids produced by Claviceps paspali were identified using ultraviolet-visible spectrophotometry and mass spectrometry. At present, no effective aetiological treatment has been described for poisoning caused by this mycotoxin, so a supportive treatment was administered, and different handling methods were applied, resulting in the complete recovery of the animals. Finally, it was concluded that unusually high humidity and temperature levels for the region triggered the development of the sclerotium generated by this fungus. |
| first_indexed | 2024-04-10T07:57:52Z |
| format | Article |
| id | doaj.art-b3209717bd434aebb22bdddc18aa9ca8 |
| institution | Directory Open Access Journal |
| issn | 0375-8427 1805-9392 |
| language | English |
| last_indexed | 2024-04-10T07:57:52Z |
| publishDate | 2023-01-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Veterinární Medicína |
| spelling | doaj.art-b3209717bd434aebb22bdddc18aa9ca82023-02-23T03:51:12ZengCzech Academy of Agricultural SciencesVeterinární Medicína0375-84271805-93922023-01-01671263864310.17221/25/2022-VETMEDvet-202212-0005Tremorgenic mycotoxicosis in cattle, caused by Claviceps paspaliN Ayala-Soldado0Lora-Benitez AJ1R Mora-Medina2Molina-Lopez AMª3Artillo-Guimera JI4Moyano-Salvago MªR5Department of Anatomy and Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, SpainDepartment of Anatomy and Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, SpainDepartment of Anatomy and Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, SpainDepartment of Anatomy and Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, SpainDepartment of Anatomy and Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, SpainDepartment of Anatomy and Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Córdoba, SpainClaviceps paspali is a fungus that mainly parasitises Paspalum dilatatum, generating a structure denominated sclerotium, in which indole-diterpenoid alkaloids are isolated. Its action mechanism is related to the inhibition of the gamma-aminobutyric acid receptor. It basically affects bovines, triggering the tremorgenic syndrome, the prevalence of this intoxication being relatively low in Europe. This work describes a clinical case on a cattle farm in Seville (southern Spain), composed of 91 bovines, 60% of which were principally affected with nervous clinical signs. The diagnosis was based on a clinical inspection of the animals, as well as of the presence of paspalum seed heads containing the sclerotia of Claviceps paspali in the plants present in the pastures. The causal agent was identified as being Claviceps paspali, which had parasitised numerous examples of Paspalum paspaloides. The indole-diterpenoid alkaloids produced by Claviceps paspali were identified using ultraviolet-visible spectrophotometry and mass spectrometry. At present, no effective aetiological treatment has been described for poisoning caused by this mycotoxin, so a supportive treatment was administered, and different handling methods were applied, resulting in the complete recovery of the animals. Finally, it was concluded that unusually high humidity and temperature levels for the region triggered the development of the sclerotium generated by this fungus.https://vetmed.agriculturejournals.cz/artkey/vet-202212-0005_tremorgenic-mycotoxicosis-in-cattle-caused-by-claviceps-paspali.phpbovinemycotoxinspaspalumsclerotiumtremor |
| spellingShingle | N Ayala-Soldado Lora-Benitez AJ R Mora-Medina Molina-Lopez AMª Artillo-Guimera JI Moyano-Salvago MªR Tremorgenic mycotoxicosis in cattle, caused by Claviceps paspali Veterinární Medicína bovine mycotoxins paspalum sclerotium tremor |
| title | Tremorgenic mycotoxicosis in cattle, caused by Claviceps paspali |
| title_full | Tremorgenic mycotoxicosis in cattle, caused by Claviceps paspali |
| title_fullStr | Tremorgenic mycotoxicosis in cattle, caused by Claviceps paspali |
| title_full_unstemmed | Tremorgenic mycotoxicosis in cattle, caused by Claviceps paspali |
| title_short | Tremorgenic mycotoxicosis in cattle, caused by Claviceps paspali |
| title_sort | tremorgenic mycotoxicosis in cattle caused by claviceps paspali |
| topic | bovine mycotoxins paspalum sclerotium tremor |
| url | https://vetmed.agriculturejournals.cz/artkey/vet-202212-0005_tremorgenic-mycotoxicosis-in-cattle-caused-by-claviceps-paspali.php |
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