Microalgae as a Sustainable, Natural-Oriented and Vegan Dermocosmetic Bioactive Ingredient: The Case of <i>Neochloris oleoabundans</i>
“Vegan” and “sustainable” characteristics are strong claim trends behind the development of innovative skincare, fragrances, and makeup products. This created a need in the market for compliant ingredients. To date, there have been no records evidencing the use of the microalgae <i>Neochloris...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | Cosmetics |
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| Online Access: | https://www.mdpi.com/2079-9284/9/1/9 |
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| author | Ana Lucía Morocho-Jácome Bruna Bertoloni dos Santos João Carlos Monteiro de Carvalho Tânia Santos de Almeida Patrícia Rijo Maria Valéria Robles Velasco Catarina Rosado André Rolim Baby |
| author_facet | Ana Lucía Morocho-Jácome Bruna Bertoloni dos Santos João Carlos Monteiro de Carvalho Tânia Santos de Almeida Patrícia Rijo Maria Valéria Robles Velasco Catarina Rosado André Rolim Baby |
| author_sort | Ana Lucía Morocho-Jácome |
| collection | DOAJ |
| description | “Vegan” and “sustainable” characteristics are strong claim trends behind the development of innovative skincare, fragrances, and makeup products. This created a need in the market for compliant ingredients. To date, there have been no records evidencing the use of the microalgae <i>Neochloris oleoabundans</i> (NA) in dermocosmetics. Therefore, we studied the applicability of such a natural compound in this context. NA was cultivated, and the scavenging activity (SA) of the NA extracts was evaluated. The highest SA was from the aqueous extract (54.8% ± 2.1%), being higher than that of the positive control. Two hydrogels were prepared with 1.0% ammonium acryloyldimethyltaurate/VP copolymer: (1) control gel; and (2) gel with a 1.0% NA aqueous extract. In vivo experiments were performed in healthy male and female volunteers with skin phototypes of II–IV. The <i>stratum corneum</i> (SC) hydration and the transepidermal water loss (TEWL) were measured in the forearm of participants to determine their biocompatibility. This parameter was determined by skin bioengineering measurements, confirming that SC hydration and TEWL were not affected by the samples. The laser Doppler measurements results showed a delayed erythema onset in the sites, where the NA hydrogel was applied. The results confirmed the biocompatibility and the anti-inflammatory activity of an innovative ingredient derived from microalgae suitable for a natural and vegan lifestyle. |
| first_indexed | 2024-03-09T22:16:32Z |
| format | Article |
| id | doaj.art-b3282fcc01964fc1a46511d7eb90ed16 |
| institution | Directory Open Access Journal |
| issn | 2079-9284 |
| language | English |
| last_indexed | 2024-03-09T22:16:32Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cosmetics |
| spelling | doaj.art-b3282fcc01964fc1a46511d7eb90ed162023-11-23T19:22:59ZengMDPI AGCosmetics2079-92842022-01-0191910.3390/cosmetics9010009Microalgae as a Sustainable, Natural-Oriented and Vegan Dermocosmetic Bioactive Ingredient: The Case of <i>Neochloris oleoabundans</i>Ana Lucía Morocho-Jácome0Bruna Bertoloni dos Santos1João Carlos Monteiro de Carvalho2Tânia Santos de Almeida3Patrícia Rijo4Maria Valéria Robles Velasco5Catarina Rosado6André Rolim Baby7Pharmacy Department, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, BrazilPharmacy Department, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, BrazilBiochemical and Pharmaceutical Technology Department, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, BrazilCBIOS—Universidade Lusófona’s Research Center for Biosciences and Health Technologies, 1749-024 Lisboa, PortugalCBIOS—Universidade Lusófona’s Research Center for Biosciences and Health Technologies, 1749-024 Lisboa, PortugalPharmacy Department, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, BrazilCBIOS—Universidade Lusófona’s Research Center for Biosciences and Health Technologies, 1749-024 Lisboa, PortugalPharmacy Department, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil“Vegan” and “sustainable” characteristics are strong claim trends behind the development of innovative skincare, fragrances, and makeup products. This created a need in the market for compliant ingredients. To date, there have been no records evidencing the use of the microalgae <i>Neochloris oleoabundans</i> (NA) in dermocosmetics. Therefore, we studied the applicability of such a natural compound in this context. NA was cultivated, and the scavenging activity (SA) of the NA extracts was evaluated. The highest SA was from the aqueous extract (54.8% ± 2.1%), being higher than that of the positive control. Two hydrogels were prepared with 1.0% ammonium acryloyldimethyltaurate/VP copolymer: (1) control gel; and (2) gel with a 1.0% NA aqueous extract. In vivo experiments were performed in healthy male and female volunteers with skin phototypes of II–IV. The <i>stratum corneum</i> (SC) hydration and the transepidermal water loss (TEWL) were measured in the forearm of participants to determine their biocompatibility. This parameter was determined by skin bioengineering measurements, confirming that SC hydration and TEWL were not affected by the samples. The laser Doppler measurements results showed a delayed erythema onset in the sites, where the NA hydrogel was applied. The results confirmed the biocompatibility and the anti-inflammatory activity of an innovative ingredient derived from microalgae suitable for a natural and vegan lifestyle.https://www.mdpi.com/2079-9284/9/1/9biocompatibilityin vitro antioxidant activityin vivo anti-inflammatorylaser Doppler flowmetrymicroalgal biotechnologysafety testing |
| spellingShingle | Ana Lucía Morocho-Jácome Bruna Bertoloni dos Santos João Carlos Monteiro de Carvalho Tânia Santos de Almeida Patrícia Rijo Maria Valéria Robles Velasco Catarina Rosado André Rolim Baby Microalgae as a Sustainable, Natural-Oriented and Vegan Dermocosmetic Bioactive Ingredient: The Case of <i>Neochloris oleoabundans</i> Cosmetics biocompatibility in vitro antioxidant activity in vivo anti-inflammatory laser Doppler flowmetry microalgal biotechnology safety testing |
| title | Microalgae as a Sustainable, Natural-Oriented and Vegan Dermocosmetic Bioactive Ingredient: The Case of <i>Neochloris oleoabundans</i> |
| title_full | Microalgae as a Sustainable, Natural-Oriented and Vegan Dermocosmetic Bioactive Ingredient: The Case of <i>Neochloris oleoabundans</i> |
| title_fullStr | Microalgae as a Sustainable, Natural-Oriented and Vegan Dermocosmetic Bioactive Ingredient: The Case of <i>Neochloris oleoabundans</i> |
| title_full_unstemmed | Microalgae as a Sustainable, Natural-Oriented and Vegan Dermocosmetic Bioactive Ingredient: The Case of <i>Neochloris oleoabundans</i> |
| title_short | Microalgae as a Sustainable, Natural-Oriented and Vegan Dermocosmetic Bioactive Ingredient: The Case of <i>Neochloris oleoabundans</i> |
| title_sort | microalgae as a sustainable natural oriented and vegan dermocosmetic bioactive ingredient the case of i neochloris oleoabundans i |
| topic | biocompatibility in vitro antioxidant activity in vivo anti-inflammatory laser Doppler flowmetry microalgal biotechnology safety testing |
| url | https://www.mdpi.com/2079-9284/9/1/9 |
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