| Summary: | Pseudo exfoliation syndrome is the most common cause of secondary open angle glaucoma wherein due to poorly understood reasons, an unknown substance, a pseudoexfoliative material, is deposited on the anterior lens capsule and other structures of the anterior segment, especially the cornea, iris, pupillary margins, angles and zonules. Fifty percent of these patients ultimately develop glaucoma. The glaucoma when developed is more aggressive, exhibits more pressure fluctuations and is more resistant to standard lines of care and management. Therefore, these cases require close follow-ups and lifelong monitoring. Cataract surgery in these cases also requires special pre-operative planning and intraoperative management because of the attendant problems like poorly dilating pupils and zonular weakness. A major concern with this condition is that the deposition of the material continues throughout the life of the patient leading to unexpected complications at any time, which warrants intensive counseling patient. After extensive internet surfing and literature search, we herein attempt to present the important features of this common, but yet under recognized and less understood disease.
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