Interleukin-33: Its Emerging Role in Allergic Diseases

Interleukin-33: Its Emerging Role in Allergic Diseases

Allergic diseases, which include asthma, allergic rhinitis (AR), chronic rhinosinusitis (CRS), atopic dermatitis (AD), food allergy (FA), allergic keratoconjunctivitis, seriously affect the quality of life of people all over the world. Recently, interleukin-33 (IL-33) has been found to play an impor...

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Bibliographic Details
Main Authors: Wen Ding, Gui-Lin Zou, Wei Zhang, Xing-Ning Lai, Hou-Wen Chen, Li-Xia Xiong
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Molecules
Subjects:
interleukin-33
allergic diseases
target therapy
asthma
Th2-type immunity
Online Access:http://www.mdpi.com/1420-3049/23/7/1665
Description
Summary:Allergic diseases, which include asthma, allergic rhinitis (AR), chronic rhinosinusitis (CRS), atopic dermatitis (AD), food allergy (FA), allergic keratoconjunctivitis, seriously affect the quality of life of people all over the world. Recently, interleukin-33 (IL-33) has been found to play an important role in these refractory disorders, mainly by inducing T helper (Th) 2 immune responses. This article reviews the mobilization and biological function of IL-33 in allergic disorders, providing novel insights for addressing these hypersensitive conditions.
ISSN:1420-3049

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