Polyphenol based hybrid nano-aggregates modified collagen fibers of biological valve leaflets to achieve enhanced mechanical, anticoagulation and anti-calcification properties

Polyphenol based hybrid nano-aggregates modified collagen fibers of biological valve leaflets to achieve enhanced mechanical, anticoagulation and anti-calcification properties

Abstract Glutaraldehyde (Glut)-crosslinked porcine pericardium and bovine pericardium are mainly consisted of collagen and widely used for the preparation of heterogenous bioprosthetic heart valves (BHV), which play an important role in the replacement therapy of severe valvular heart disease, while...

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Bibliographic Details
Main Authors: Shufen Li, Shiying Lang, Zhiqian Chen, Jingruo Chen, Weihua Zhuang, Yangrui Du, Yawen Yao, Gongyan Liu, Mao Chen
Format: Article
Language:English
Published: SpringerOpen 2022-10-01
Series:Journal of Leather Science and Engineering
Subjects:
Tannic acid
Bioprosthetic heart valve
Antibacterial and anti-calcification
Online Access:https://doi.org/10.1186/s42825-022-00105-3

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