Pharmacological activities of limonin from Khasi Mandarin as therapeutic applications
Khasi Mandarin (Citrus reticulata) is a unique fruit usually cultivated in high terrains regions of North-East India. They are different from ordinary orange in terms of its biochemical content (limonin, secondary metabolites), pharmacological activities, and physicochemical appearance (bright orang...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Pharmacological Research - Modern Chinese Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667142522001415 |
| _version_ | 1828091453918674944 |
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| author | Yengkhom Disco Singh Debasmita Das Sunanya Das Kabyashree Diptimayee Swain Srimay Pradhan Punuri Jayasekhar Babu |
| author_facet | Yengkhom Disco Singh Debasmita Das Sunanya Das Kabyashree Diptimayee Swain Srimay Pradhan Punuri Jayasekhar Babu |
| author_sort | Yengkhom Disco Singh |
| collection | DOAJ |
| description | Khasi Mandarin (Citrus reticulata) is a unique fruit usually cultivated in high terrains regions of North-East India. They are different from ordinary orange in terms of its biochemical content (limonin, secondary metabolites), pharmacological activities, and physicochemical appearance (bright orange in color, hard peel, sweet aromatic juice). It has high nutritional values (NV) by enriching beta carotene as powerful antioxidant for scavenging free radicals, magnesium for blood pressure regulation, potassium for healthy cardio vascular functions, thiamin for energy conversion from food and vitamin C as immune enhancer. Despite its NV, limonin an aglycones and glycosides are largely available in Khasi Mandarin. Presence of this compound in Khasi Mandarin display numerous pharmacological activities like antimicrobial, antioxidant, anticancer, antidiabetic, anti-inflammatory, analgesic, antibacterial, anti-virus, liver protection and pesticidal. In this review, we discussed not only about the morphological aspects but detailed focused has been given on the nutritional value of Khasi mandarin, post-harvest disease and its management, metabolism and bioactive functions of the limonin as therapeutic applications. |
| first_indexed | 2024-04-11T06:13:18Z |
| format | Article |
| id | doaj.art-b32fc9d9afe04241a209a96d387a3660 |
| institution | Directory Open Access Journal |
| issn | 2667-1425 |
| language | English |
| last_indexed | 2024-04-11T06:13:18Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pharmacological Research - Modern Chinese Medicine |
| spelling | doaj.art-b32fc9d9afe04241a209a96d387a36602022-12-22T04:41:09ZengElsevierPharmacological Research - Modern Chinese Medicine2667-14252022-12-015100181Pharmacological activities of limonin from Khasi Mandarin as therapeutic applicationsYengkhom Disco Singh0Debasmita Das1Sunanya Das2Kabyashree Diptimayee Swain3Srimay Pradhan4Punuri Jayasekhar Babu5Department of Post-Harvest Technology, College of Horticulture and Forestry, Central Agricultural University, Pasighat, 791102 Arunachal Pradesh, India; Corresponding author at: Department of Post-Harvest Technology, College of Horticulture and Forestry, Central Agricultural University, Pasighat, 791102 Arunachal Pradesh, India.Department of Botany, School of Applied Sciences, Centurion University of Technology and Management, Odisha, IndiaDepartment of Botany, School of Applied Sciences, Centurion University of Technology and Management, Odisha, IndiaDepartment of Botany, School of Applied Sciences, Centurion University of Technology and Management, Odisha, IndiaDepartment of Botany, School of Applied Sciences, Centurion University of Technology and Management, Odisha, IndiaDepartment of Biotechnology, Pachhunga University College, Mizoram University (A Central University) Aizawl, 796001 Mizoram, India; Co-corresponding author at: Department of Biotechnology, Pachhunga University College, Mizoram University (A Central University) Aizawl, 796001 Mizoram, India.Khasi Mandarin (Citrus reticulata) is a unique fruit usually cultivated in high terrains regions of North-East India. They are different from ordinary orange in terms of its biochemical content (limonin, secondary metabolites), pharmacological activities, and physicochemical appearance (bright orange in color, hard peel, sweet aromatic juice). It has high nutritional values (NV) by enriching beta carotene as powerful antioxidant for scavenging free radicals, magnesium for blood pressure regulation, potassium for healthy cardio vascular functions, thiamin for energy conversion from food and vitamin C as immune enhancer. Despite its NV, limonin an aglycones and glycosides are largely available in Khasi Mandarin. Presence of this compound in Khasi Mandarin display numerous pharmacological activities like antimicrobial, antioxidant, anticancer, antidiabetic, anti-inflammatory, analgesic, antibacterial, anti-virus, liver protection and pesticidal. In this review, we discussed not only about the morphological aspects but detailed focused has been given on the nutritional value of Khasi mandarin, post-harvest disease and its management, metabolism and bioactive functions of the limonin as therapeutic applications.http://www.sciencedirect.com/science/article/pii/S2667142522001415Khasi mandarinPost-harvestNutritional valuesLimoninPharmacological activitiesTherapeutic |
| spellingShingle | Yengkhom Disco Singh Debasmita Das Sunanya Das Kabyashree Diptimayee Swain Srimay Pradhan Punuri Jayasekhar Babu Pharmacological activities of limonin from Khasi Mandarin as therapeutic applications Pharmacological Research - Modern Chinese Medicine Khasi mandarin Post-harvest Nutritional values Limonin Pharmacological activities Therapeutic |
| title | Pharmacological activities of limonin from Khasi Mandarin as therapeutic applications |
| title_full | Pharmacological activities of limonin from Khasi Mandarin as therapeutic applications |
| title_fullStr | Pharmacological activities of limonin from Khasi Mandarin as therapeutic applications |
| title_full_unstemmed | Pharmacological activities of limonin from Khasi Mandarin as therapeutic applications |
| title_short | Pharmacological activities of limonin from Khasi Mandarin as therapeutic applications |
| title_sort | pharmacological activities of limonin from khasi mandarin as therapeutic applications |
| topic | Khasi mandarin Post-harvest Nutritional values Limonin Pharmacological activities Therapeutic |
| url | http://www.sciencedirect.com/science/article/pii/S2667142522001415 |
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