Targeting STAT3 and oxidative phosphorylation in oncogene-addicted tumors

Drug resistance invariably limits the response of oncogene-addicted cancer cells to targeted therapy. The upregulation of signal transducer and activator of transcription 3 (STAT3) has been implicated as a mechanism of drug resistance in a range of oncogene-addicted cancers. However, the development...

Full description

Bibliographic Details
Main Authors: Matilda Lee, Jayshree L. Hirpara, Jie-Qing Eu, Gautam Sethi, Lingzhi Wang, Boon-Cher Goh, Andrea L. Wong
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S221323171830908X